Summary from GEO: "LY6E is an antiviral restriction factor that inhibits coronavirus spike-mediated fusion, but the cell types in vivo that require LY6E for protection from respiratory coronavirus infection are unknown. Here, we used a panel of seven conditional Ly6e knockout mice to define which Ly6e-expressing cells confer control of airway infection by murine coronavirus and SARS-CoV-2. Loss...

Summary from GEO: "The goal of this study is to compare the transcriptomes of memory and naïve B cells, and provide a resource for single cell analysis of murine B cells during influenza infection." Overall design from GEO: "Standard droplet-based single cell RNA sequencing of naïve and memory B cells done via 10X and analyzed with Seurat."