MaTAR25 lncRNA regulates the Tensin1 gene to impact breast cancer progression

Authors

Chang, Kung-Chi

Diermeier, Sarah D

Spector, David L.

Description

Summary from the GEO: "Misregulation of long non-coding RNA genes has been linked to a wide variety of cancer types. Here we report on Mammary Tumor Associated RNA 25 (MaTAR25), a nuclear enriched and chromatin associated lncRNA that plays a role in mammary tumor cell proliferation, migration, and invasion, both in vitro and in vivo. MaTAR25 functions by interacting with purine rich element binding...

Subject

Breast Neoplasms

DNA-Binding Proteins

RNA, Long Noncoding

Tensins

Access Rights

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