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Results Found: 11
  • Colorectal Adenocarcinoma (TCGA, PanCancer Atlas) data

    Description

    This dataset contains summary data visualizations and clinical data from a broad sampling of 594 colorectal adenocarcinomas from 594 patients. The data was gathered as part of the PanCancer Atlas initiative, which aims to answer big, overarching questions about cancer by examining the full set of tumors characterized in the robust TCGA dataset. The clinical data includes mutation count, information...

    Subject
    Adenocarcinoma, Mucinous
    Colonic Neoplasms
    Colorectal Neoplasms
    DNA Mutational Analysis
    Rectal Neoplasms
    Access Rights
    Free to All
  • MSK-IMPACT Clinical Sequencing Cohort (MSKCC, Nat Med 2017): Targeted sequencing of 10,000 clinical cases using the MSK-IMPACT assay

    Description

    This dataset contains summary data visualizations and clinical data from the targeted sequencing of 10,000 clinical cases using the MSK-IMPACT assay. The clinical data includes mutation count, information about mutated genes, tumor mutational burden calculations, tissue site from which the sample was derived, tumor purity among other relevant data points. The data set also includes copy-number segment...

    Subject
    Adenocarcinoma
    Adenocarcinoma of Lung
    Adenocarcinoma, Mucinous
    Breast Neoplasms
    Carcinoma, Ductal, Breast
    Carcinoma, Hepatocellular
    Carcinoma, Lobular
    Carcinoma, Non-Small-Cell Lung
    Carcinoma, Renal Cell
    Carcinoma, Squamous Cell
    Carcinosarcoma
    Cholangiocarcinoma
    Colonic Neoplasms
    Colorectal Neoplasms
    Cystadenocarcinoma, Serous
    DNA Mutational Analysis
    Gallbladder Neoplasms
    Glioblastoma
    Liposarcoma
    Lung Neoplasms
    Lymphoma, Follicular
    Melanoma
    Mesothelioma
    Neoplasms, Squamous Cell
    Neurofibroma
    Oligodendroglioma
    Osteosarcoma
    Ovarian Neoplasms
    Pancreatic Neoplasms
    Prostatic Neoplasms
    Rectal Neoplasms
    Sarcoma
    Sarcoma, Synovial
    Squamous Cell Carcinoma of Head and Neck
    Stomach Neoplasms
    Thyroid Cancer, Papillary
    Urinary Bladder Neoplasms
    Uterine Neoplasms
    Uveal Neoplasms
    Access Rights
    Free to All
  • SUMMIT - Neratinib Basket Study (Multi-Institute, Nature 2018): MSK-IMPACT sequencing of 86 patients with HER2- and HER3-mutant cancers

    Description

    This dataset contains summary data visualizations and clinical data from a broad sampling of HER2- and HER3-mutant tumors. The data was generated utilizing the MSK-IMPACT targeted sequencing test. The clinical data includes tumor type (based on the opensource OncoTree ontology developed at MSK), mutation count, information about mutated genes, Amplification Status, Best objective response rate, Bubble...

    Subject
    Breast Neoplasms
    Carcinoma, Hepatocellular
    Carcinoma, Non-Small-Cell Lung
    Carcinoma, Renal Cell
    Colorectal Neoplasms
    DNA Mutational Analysis
    Endometrial Neoplasms
    Esophageal Neoplasms
    Genes, erbB
    Genes, erbB-2
    Melanoma
    Ovarian Neoplasms
    Pancreatic Neoplasms
    Salivary Gland Neoplasms
    Sarcoma
    Skin Neoplasms
    Urinary Bladder Neoplasms
    Uterine Cervical Neoplasms
    Access Rights
    Free to All
  • NCI-60 Cell Lines (NCI, Cancer Res 2012): Whole-exome sequencing of 67 samples by NCI-60 cell line project

    Description

    This dataset contains summary data visualizations and clinical data from 67 samples from 67 patients as part an NCI-60 cell line project to compile NCI-60 cell line high-throughput and high-content data into CellMiner, a genomic and pharmacologic database created by the National Cancer Center Institute. The clinical data includes deidentified patient and sample IDs, mutation counts, detailed cancer...

    Subject
    Adenocarcinoma
    Brain Neoplasms
    Breast Neoplasms
    Carcinoma, Renal Cell
    Colorectal Neoplasms
    DNA Mutational Analysis
    Leukemia, Myeloid
    Lung Neoplasms
    Melanoma
    Ovarian Neoplasms
    Prostatic Neoplasms
    Access Rights
    Free to All
  • Colorectal Adenocaranoma (TCGA, Firehose Legacy)

    Description

    TCGA Colorectal Adenocarcinoma. Source data from GDAC Firehose. Previously known as TCGA Provisional. This dataset contains summary data visualizations and clinical data from a broad sampling of 640 carcinomas from 636 patients. The data was gathered as part of the Broad Institute of MIT and Harvard Firehose initiative, a cancer analysis pipeline. The clinical data includes mutation count, information...

    Subject
    Adenocarcinoma
    Colorectal Neoplasms
    DNA Mutational Analysis
    Access Rights
    Free to All
  • Regenerative origin of metastasis stem cells

    Authors
    Ganesh, Karuna
    Massagué, Joan
    Koche, Richard Patrick
    Reuter, Vincent Patrick
    Description

    Author summary from Gene Expression Omnibus: "Assaying binding of REST to DNA with ChIP-seq reveals the role of REST in transcriptional regulation in colorectal cancer (CRC) metastatic stem cells (MetSCs). REST is especially relevant to regulation of L1CAM expression." Overall Design: "ChIP-seq of binding of REST to DNA." Abstract summary: "Metastasis-initiating cells with stem-like properties drive...

    Subject
    Colorectal Neoplasms
    Neoplastic Stem Cells
    Access Rights
    Free to All
  • The Angiosarcoma Project (Provisional): an ongoing patient-driven initiative.

    Description

    Dataset Summary Description: "This provisional dataset is currently derived from 83 samples, including tumor specimens (FFPE and cfDNA) from 62 angiosarcoma patients subjected to WES (along with matched germline WES). This study includes genomic data, patient-reported data (pre-pended as PRD), medical record data (MedR), and pathology report data (PATH). As these data were generated in a research...

    Subject
    Basal Cell Carcinoma
    Breast Neoplasms
    Colorectal Neoplasms
    Hemangiosarcoma
    Hodgkin Disease
    Leukemia, Lymphocytic, Chronic, B-Cell
    Prostatic Neoplasms
    Rectal Neoplasms
    Skin Neoplasms
    Thyroid Neoplasms
    Uterine Neoplasms
    Vulvar Neoplasms
    Access Rights
    Free to All
  • Metastatic Colorectal Cancer (MSKCC, Cancer Cell 2018): Targeted sequencing of 1,134 metastatic colorectal tumor/normal pairs.

    Description

    This dataset contains the summary data visualizations and clinical data from targeted sequencing of 1,099 metastatic colorectal tumor/normal pairs from 1,134 patients. Clinical data includes: Number of Samples Per Patient, Mutation Count, Fraction Genome Altered, Overall Survival Status, Sample Type, Sex, Age at Diagnosis, Chemo Exposure of sequenced specimen, First Site of Metastasis, Gene Panel,...

    Subject
    Colonic Neoplasms
    Colorectal Neoplasms
    Access Rights
    Free to All
  • Global proteome analysis of paired colorectal cancer sample using LC-MS/MS

    Authors
    Tanaka, Atsushi
    Roehrl, Michael H.
    Description

    Description from PRIDE: "To find differentially expressed protein in colorectal cancer compared with normal colon tissue, we performed global proteome analysis using LC-MS."

    Subject
    Biomarkers, Tumor
    Colorectal Neoplasms
    Liquid Chromatography-Mass Spectrometry
    Mucous Membrane
    Prolyl Hydroxylases
    Survival Analysis
    Access Rights
    Free to All
  • Colorectal cancer proteome project for biomarke search and development of clinical test

    Authors
    Tanaka, Atsushi
    Roehrl, Michael H.
    Description

    Description from PRIDE: "To find differentially expressed protein in colorectal cancer compared with normal colon tissue, we performed global proteome analysis using LC-MS."

    Subject
    Biomarkers, Tumor
    Colorectal Neoplasms
    Liquid Chromatography-Mass Spectrometry
    Proteome
    Access Rights
    Free to All