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Results Found: 13
  • An Open Library of Human Kinase Domain Constructs for Automated Bacterial Expression

    Authors
    Albanese, Steven Kyle
    Parton, Daniel Lawrence
    Isik, Mehtap
    Rodriguez-Laureano, Lucelenie
    7 more author(s)...
    Description

    Source code, assay data, full expression results for all ABL1 constructs, wild-type kinases, and ABL1 and SRC mutants, plasmid libraries, and other supporting material for the generation of a library of human kinase domain constructs for automated bacterial expression. From the publication abstract, "Kinases play a critical role in cellular signaling and are dysregulated in a number of diseases,...

    Subject
    Bacteria/metabolism
    Binding sites
    Escherichia coli/metabolism
    Phosphorylation
    Protein Structure, Secondary
    Protein-Tyrosine Kinases
    Proto-Oncogene Proteins c-abl
    src-Family Kinases
    Access Rights
    Free to All
    Fee Required
  • Cryo-EM structure of the mitochondrial calcium uniporter MCU from the fungus Cyphellophora europaea

    Authors
    Long, Stephen Barstow
    Baradaran, Rozbeh
    Wang, Chongyuan
    Description

    This deposit in the Research Collaboratory for Structural Bioinformatics Protein Data Base (PDB) includes cryogenic electron microscopy data identifying mitochondrial calcium uniporter MCU from the fungus Cyphellophora europaea. The main summary display for this entry includes information on the experimental method, protein source, macromolecules and small molecules included in the deposit, and version...

    Subject
    Ascomycota
    Calcium Channels
    Protein Conformation
    Protein Structure, Quaternary
    Protein Structure, Secondary
    Protein Structure, Tertiary
    Access Rights
    Free to All
  • Cryo-EM structure of Csm-crRNA-target RNA ternary bigger complex in complex with cA4 in type III-A CRISPR-Cas system

    Authors
    Jia, Ning
    Patel, Dinshaw J.
    Description

    This deposit in the Research Collaboratory for Structural Bioinformatics Protein Data Base (PDB) includes cryogenic electron microscopy data identifying the structure of Cryo-EM structure of Csm-crRNA-target RNA ternary bigger complex in complex with cA4 in type III-A CRISPR-Cas system. The main summary display for this entry includes an experimental data snapshot, protein source, macromolecules and...

    Subject
    Clustered Regularly Interspaced Short Palindromic Repeats
    CRISPR-Cas Systems
    Cryoelectron Microscopy
    Protein Conformation
    Protein Structure, Quaternary
    Protein Structure, Secondary
    Protein Structure, Tertiary
    Ribonucleases / chemistry
    Access Rights
    Free to All
  • Cryo-EM structure of Csm-crRNA-target RNA ternary complex in complex with cA4 in type III-A CRISPR-Cas system

    Authors
    Jia, Ning
    Patel, Dinshaw J.
    Description

    This deposit in the Research Collaboratory for Structural Bioinformatics Protein Data Base (PDB) includes cryogenic electron microscopy data identifying the structure of Csm-crRNA-target RNA ternary complex in complex with cA4 in type III-A CRISPR-Cas system. The main summary display for this entry includes an experimental data snapshot, protein source, macromolecules and small molecules included...

    Subject
    Clustered Regularly Interspaced Short Palindromic Repeats
    CRISPR-Cas Systems
    Cryoelectron Microscopy
    Protein Conformation
    Protein Structure, Quaternary
    Protein Structure, Secondary
    Protein Structure, Tertiary
    Ribonucleases / chemistry
    Access Rights
    Free to All
  • Cryo-EM structure of Csm-crRNA-target RNA ternary complex in complex with AMPPNP in type III-A CRISPR-Cas system

    Authors
    Jia, Ning
    Patel, Dinshaw J.
    Description

    This deposit in the Research Collaboratory for Structural Bioinformatics Protein Data Base (PDB) includes cryogenic electron microscopy data identifying the structure of Csm-crRNA-target RNA ternary complex in complex with AMPPNP in type III-A CRISPR-Cas system. The main summary display for this entry includes an experimental data snapshot, protein source, macromolecules and small molecules included...

    Subject
    Clustered Regularly Interspaced Short Palindromic Repeats
    CRISPR-Cas Systems
    Cryoelectron Microscopy
    Protein Conformation
    Protein Structure, Quaternary
    Protein Structure, Secondary
    Protein Structure, Tertiary
    Ribonucleases / chemistry
    Access Rights
    Free to All
  • Crystal structure of Csm1-Csm4 cassette in complex with cA3

    Authors
    Jia, Ning
    Patel, Dinshaw J.
    Description

    This deposit in the Research Collaboratory for Structural Bioinformatics Protein Data Base (PDB) includes cryogenic electron microscopy data identifying the structure of Crystal structure of Csm1-Csm4 cassette in complex with cA3. The main summary display for this entry includes an experimental data snapshot, protein source, macromolecules and small molecules included in the deposit, and version history...

    Subject
    Carbonic Anhydrases
    Clustered Regularly Interspaced Short Palindromic Repeats
    Cryoelectron Microscopy
    Escherichia coli Proteins
    Nuclear Proteins
    Protein Conformation
    Protein Structure, Quaternary
    Protein Structure, Secondary
    Protein Structure, Tertiary
    Access Rights
    Free to All
  • Crystal structure of Csm1-Csm4 cassette in complex with cA4

    Authors
    Jia, Ning
    Patel, Dinshaw J.
    Description

    This deposit in the Research Collaboratory for Structural Bioinformatics Protein Data Base (PDB) includes cryogenic electron microscopy data identifying the structure of Crystal structure of Csm1-Csm4 cassette in complex with cA4. The main summary display for this entry includes an experimental data snapshot, protein source, macromolecules and small molecules included in the deposit, and version history...

    Subject
    Carbonic Anhydrases
    Clustered Regularly Interspaced Short Palindromic Repeats
    Cryoelectron Microscopy
    Escherichia coli Proteins
    Nuclear Proteins
    Protein Conformation
    Protein Structure, Quaternary
    Protein Structure, Secondary
    Protein Structure, Tertiary
    Access Rights
    Free to All
  • Crystal structure of Csm1-Csm4 cassette in complex with one ATP

    Authors
    Jia, Ning
    Patel, Dinshaw J.
    Description

    This deposit in the Research Collaboratory for Structural Bioinformatics Protein Data Base (PDB) includes cryogenic electron microscopy data identifying the Crystal structure of Csm1-Csm4 cassette in complex with one ATP. The main summary display for this entry includes an experimental data snapshot, protein source, macromolecules and small molecules included in the deposit, and version history and...

    Subject
    Adenosine Triphosphate
    Clustered Regularly Interspaced Short Palindromic Repeats
    Cryoelectron Microscopy
    Escherichia coli Proteins
    Nuclear Proteins
    Protein Conformation
    Protein Structure, Quaternary
    Protein Structure, Secondary
    Protein Structure, Tertiary
    Access Rights
    Free to All
  • Crystal structure of Csm1-Csm4 cassette in complex with pppApApA

    Authors
    Jia, Ning
    Patel, Dinshaw J.
    Description

    This deposit in the Research Collaboratory for Structural Bioinformatics Protein Data Base (PDB) includes cryogenic electron microscopy data identifying the structure of Crystal structure of Csm1-Csm4 cassette in complex with pppApApA. The main summary display for this entry includes an experimental data snapshot, protein source, macromolecules and small molecules included in the deposit, and version...

    Subject
    Cryoelectron Microscopy
    Escherichia coli Proteins
    Nuclear Proteins
    Protein Conformation
    Protein Structure, Quaternary
    Protein Structure, Secondary
    Protein Structure, Tertiary
    Access Rights
    Free to All
  • Crystal structure of Csm1-Csm4 cassette in complex with pppApA

    Authors
    Jia, Ning
    Patel, Dinshaw J.
    Description

    This deposit in the Research Collaboratory for Structural Bioinformatics Protein Data Base (PDB) includes cryogenic electron microscopy data identifying the structure of Crystal structure of Csm1-Csm4 cassette in complex with pppApA. The main summary display for this entry includes an experimental data snapshot, protein source, macromolecules and small molecules included in the deposit, and version...

    Subject
    Cryoelectron Microscopy
    Escherichia coli Proteins
    Nuclear Proteins
    Protein Conformation
    Protein Structure, Quaternary
    Protein Structure, Secondary
    Protein Structure, Tertiary
    Access Rights
    Free to All