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Small RNAs from 11 Drosophila species
- Authors
- Mohammed, JaavedFlynt, Alex SLai, Eric C
- Description
Summary from the GEO: "Annotation of small RNAs from 11 Drosophila species for the purpose of non-coding RNA annotation and comparative genomics assessment." Overall design from the GEO: "Small RNA samples from 11 Drosophila species." Abstract Summary: "To assess miRNA evolution across the Drosophila genus, we analyzed several billion small RNA reads across 12 fruit fly species. These data permit...
- Subject
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DrosophilaGenomicsRNA, Small UntranslatedRNA, Untranslated
- Access Rights
- Free to All
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Regulatory logic of endogenous RNAi in silencing de novo genomic conflicts
- Authors
- Vedanayagam, JeffreyLin, Ching-JungPapareddy, RanjithNodine, Michael3 more author(s)...
- Description
Summary from GEO: "Although the biological utilities of endogenous RNAi (endo-RNAi) have been largely elusive, recent studies reveal its critical role in the non-model fruitfly Drosophila simulans to suppress selfish genes, whose unchecked activities can severely impair spermatogenesis. In particular, hairpin RNA (hpRNA) loci generate endo-siRNAs that suppress evolutionary novel, X-linked, meiotic...
- Subject
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Gene ExpressionRNA InterferenceRNA-SeqRNA, Small InterferingSpermatogenesis
- Access Rights
- Free to All