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Results Found: 7
  • Cryo-EM structure of Csm-crRNA-target RNA ternary bigger complex in complex with cA4 in type III-A CRISPR-Cas system

    Authors
    Jia, Ning
    Patel, Dinshaw J.
    Description

    This deposit in the Research Collaboratory for Structural Bioinformatics Protein Data Base (PDB) includes cryogenic electron microscopy data identifying the structure of Cryo-EM structure of Csm-crRNA-target RNA ternary bigger complex in complex with cA4 in type III-A CRISPR-Cas system. The main summary display for this entry includes an experimental data snapshot, protein source, macromolecules and...

    Subject
    Clustered Regularly Interspaced Short Palindromic Repeats
    CRISPR-Cas Systems
    Cryoelectron Microscopy
    Protein Conformation
    Protein Structure, Quaternary
    Protein Structure, Secondary
    Protein Structure, Tertiary
    Ribonucleases / chemistry
    Access Rights
    Free to All
  • Cryo-EM structure of Csm-crRNA-target RNA ternary complex in complex with cA4 in type III-A CRISPR-Cas system

    Authors
    Jia, Ning
    Patel, Dinshaw J.
    Description

    This deposit in the Research Collaboratory for Structural Bioinformatics Protein Data Base (PDB) includes cryogenic electron microscopy data identifying the structure of Csm-crRNA-target RNA ternary complex in complex with cA4 in type III-A CRISPR-Cas system. The main summary display for this entry includes an experimental data snapshot, protein source, macromolecules and small molecules included...

    Subject
    Clustered Regularly Interspaced Short Palindromic Repeats
    CRISPR-Cas Systems
    Cryoelectron Microscopy
    Protein Conformation
    Protein Structure, Quaternary
    Protein Structure, Secondary
    Protein Structure, Tertiary
    Ribonucleases / chemistry
    Access Rights
    Free to All
  • Crystal structure of Csm1-Csm4 cassette in complex with cA3

    Authors
    Jia, Ning
    Patel, Dinshaw J.
    Description

    This deposit in the Research Collaboratory for Structural Bioinformatics Protein Data Base (PDB) includes cryogenic electron microscopy data identifying the structure of Crystal structure of Csm1-Csm4 cassette in complex with cA3. The main summary display for this entry includes an experimental data snapshot, protein source, macromolecules and small molecules included in the deposit, and version history...

    Subject
    Carbonic Anhydrases
    Clustered Regularly Interspaced Short Palindromic Repeats
    Cryoelectron Microscopy
    Escherichia coli Proteins
    Nuclear Proteins
    Protein Conformation
    Protein Structure, Quaternary
    Protein Structure, Secondary
    Protein Structure, Tertiary
    Access Rights
    Free to All
  • Crystal structure of Csm1-Csm4 cassette in complex with cA4

    Authors
    Jia, Ning
    Patel, Dinshaw J.
    Description

    This deposit in the Research Collaboratory for Structural Bioinformatics Protein Data Base (PDB) includes cryogenic electron microscopy data identifying the structure of Crystal structure of Csm1-Csm4 cassette in complex with cA4. The main summary display for this entry includes an experimental data snapshot, protein source, macromolecules and small molecules included in the deposit, and version history...

    Subject
    Carbonic Anhydrases
    Clustered Regularly Interspaced Short Palindromic Repeats
    Cryoelectron Microscopy
    Escherichia coli Proteins
    Nuclear Proteins
    Protein Conformation
    Protein Structure, Quaternary
    Protein Structure, Secondary
    Protein Structure, Tertiary
    Access Rights
    Free to All
  • Crystal structure of Csm1-Csm4 cassette in complex with pppApApA

    Authors
    Jia, Ning
    Patel, Dinshaw J.
    Description

    This deposit in the Research Collaboratory for Structural Bioinformatics Protein Data Base (PDB) includes cryogenic electron microscopy data identifying the structure of Crystal structure of Csm1-Csm4 cassette in complex with pppApApA. The main summary display for this entry includes an experimental data snapshot, protein source, macromolecules and small molecules included in the deposit, and version...

    Subject
    Cryoelectron Microscopy
    Escherichia coli Proteins
    Nuclear Proteins
    Protein Conformation
    Protein Structure, Quaternary
    Protein Structure, Secondary
    Protein Structure, Tertiary
    Access Rights
    Free to All
  • Crystal structure of Csm1-Csm4 cassette in complex with pppApA

    Authors
    Jia, Ning
    Patel, Dinshaw J.
    Description

    This deposit in the Research Collaboratory for Structural Bioinformatics Protein Data Base (PDB) includes cryogenic electron microscopy data identifying the structure of Crystal structure of Csm1-Csm4 cassette in complex with pppApA. The main summary display for this entry includes an experimental data snapshot, protein source, macromolecules and small molecules included in the deposit, and version...

    Subject
    Cryoelectron Microscopy
    Escherichia coli Proteins
    Nuclear Proteins
    Protein Conformation
    Protein Structure, Quaternary
    Protein Structure, Secondary
    Protein Structure, Tertiary
    Access Rights
    Free to All
  • TMEM41B is a pan-flavivirus host factor

    Authors
    Hoffmann, H.-Heinrich
    Schneider, William M.
    Rozen-Gagnon, Kathryn
    Miles, Linde A.
    10 more author(s)...
    Description

    Summary from the GEO: "Flaviviruses pose a constant threat to human health. These RNA viruses are transmitted by the bite of infected mosquitoes and ticks and regularly cause outbreaks. To identify host factors required for flavivirus infection we performed full-genome loss of function CRISPR-Cas9 screens. Based on these results we focused our efforts on characterizing the roles that TMEM41B and VMP1...

    Subject
    CRISPR-Cas Systems
    Flavivirus
    Flavivirus Infections
    Membrane Proteins
    Polymorphism, Single Nucleotide
    Virus Replication
    Access Rights
    Free to All