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Cryo-EM structure of Csm-crRNA-target RNA ternary bigger complex in complex with cA4 in type III-A CRISPR-Cas system
- Authors
- Jia, NingPatel, Dinshaw J.
- Description
This deposit in the Research Collaboratory for Structural Bioinformatics Protein Data Base (PDB) includes cryogenic electron microscopy data identifying the structure of Cryo-EM structure of Csm-crRNA-target RNA ternary bigger complex in complex with cA4 in type III-A CRISPR-Cas system. The main summary display for this entry includes an experimental data snapshot, protein source, macromolecules and...
- Subject
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Clustered Regularly Interspaced Short Palindromic RepeatsCRISPR-Cas SystemsCryoelectron MicroscopyProtein ConformationProtein Structure, QuaternaryProtein Structure, SecondaryProtein Structure, TertiaryRibonucleases / chemistry
- Access Rights
- Free to All
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Cryo-EM structure of Csm-crRNA-target RNA ternary complex in complex with cA4 in type III-A CRISPR-Cas system
- Authors
- Jia, NingPatel, Dinshaw J.
- Description
This deposit in the Research Collaboratory for Structural Bioinformatics Protein Data Base (PDB) includes cryogenic electron microscopy data identifying the structure of Csm-crRNA-target RNA ternary complex in complex with cA4 in type III-A CRISPR-Cas system. The main summary display for this entry includes an experimental data snapshot, protein source, macromolecules and small molecules included...
- Subject
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Clustered Regularly Interspaced Short Palindromic RepeatsCRISPR-Cas SystemsCryoelectron MicroscopyProtein ConformationProtein Structure, QuaternaryProtein Structure, SecondaryProtein Structure, TertiaryRibonucleases / chemistry
- Access Rights
- Free to All
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Crystal structure of Csm1-Csm4 cassette in complex with pppApApA
- Authors
- Jia, NingPatel, Dinshaw J.
- Description
This deposit in the Research Collaboratory for Structural Bioinformatics Protein Data Base (PDB) includes cryogenic electron microscopy data identifying the structure of Crystal structure of Csm1-Csm4 cassette in complex with pppApApA. The main summary display for this entry includes an experimental data snapshot, protein source, macromolecules and small molecules included in the deposit, and version...
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Cryoelectron MicroscopyEscherichia coli ProteinsNuclear ProteinsProtein ConformationProtein Structure, QuaternaryProtein Structure, SecondaryProtein Structure, Tertiary
- Access Rights
- Free to All
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Crystal structure of Csm1-Csm4 cassette in complex with pppApA
- Authors
- Jia, NingPatel, Dinshaw J.
- Description
This deposit in the Research Collaboratory for Structural Bioinformatics Protein Data Base (PDB) includes cryogenic electron microscopy data identifying the structure of Crystal structure of Csm1-Csm4 cassette in complex with pppApA. The main summary display for this entry includes an experimental data snapshot, protein source, macromolecules and small molecules included in the deposit, and version...
- Subject
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Cryoelectron MicroscopyEscherichia coli ProteinsNuclear ProteinsProtein ConformationProtein Structure, QuaternaryProtein Structure, SecondaryProtein Structure, Tertiary
- Access Rights
- Free to All
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Crystal structure of Csm1-Csm4 cassette in complex with cA3
- Authors
- Jia, NingPatel, Dinshaw J.
- Description
This deposit in the Research Collaboratory for Structural Bioinformatics Protein Data Base (PDB) includes cryogenic electron microscopy data identifying the structure of Crystal structure of Csm1-Csm4 cassette in complex with cA3. The main summary display for this entry includes an experimental data snapshot, protein source, macromolecules and small molecules included in the deposit, and version history...
- Subject
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Carbonic AnhydrasesClustered Regularly Interspaced Short Palindromic RepeatsCryoelectron MicroscopyEscherichia coli ProteinsNuclear ProteinsProtein ConformationProtein Structure, QuaternaryProtein Structure, SecondaryProtein Structure, Tertiary
- Access Rights
- Free to All
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Crystal structure of Csm1-Csm4 cassette in complex with cA4
- Authors
- Jia, NingPatel, Dinshaw J.
- Description
This deposit in the Research Collaboratory for Structural Bioinformatics Protein Data Base (PDB) includes cryogenic electron microscopy data identifying the structure of Crystal structure of Csm1-Csm4 cassette in complex with cA4. The main summary display for this entry includes an experimental data snapshot, protein source, macromolecules and small molecules included in the deposit, and version history...
- Subject
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Carbonic AnhydrasesClustered Regularly Interspaced Short Palindromic RepeatsCryoelectron MicroscopyEscherichia coli ProteinsNuclear ProteinsProtein ConformationProtein Structure, QuaternaryProtein Structure, SecondaryProtein Structure, Tertiary
- Access Rights
- Free to All
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TMEM41B is a pan-flavivirus host factor
- Authors
- Hoffmann, H.-HeinrichSchneider, William M.Rozen-Gagnon, KathrynMiles, Linde A.10 more author(s)...
- Description
Summary from the GEO: "Flaviviruses pose a constant threat to human health. These RNA viruses are transmitted by the bite of infected mosquitoes and ticks and regularly cause outbreaks. To identify host factors required for flavivirus infection we performed full-genome loss of function CRISPR-Cas9 screens. Based on these results we focused our efforts on characterizing the roles that TMEM41B and VMP1...
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CRISPR-Cas SystemsFlavivirusFlavivirus InfectionsMembrane ProteinsPolymorphism, Single NucleotideVirus Replication
- Access Rights
- Free to All