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Breast Invasive Carcinoma (TCGA, PanCancer Atlas) data
- Description
This dataset contains summary data visualizations and clinical data from a broad sampling of 1,084 breast invasive carcinomas from 1,084 patients. The data was gathered as part of the PanCancer Atlas initiative, which aims to answer big, overarching questions about cancer by examining the full set of tumors characterized in the robust TCGA dataset. The clinical data includes mutation count, information...
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Breast NeoplasmsCarcinoma, Ductal, BreastCarcinoma, LobularDNA Mutational Analysis
- Access Rights
- Free to All
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SUMMIT - Neratinib Basket Study (Multi-Institute, Nature 2018): MSK-IMPACT sequencing of 86 patients with HER2- and HER3-mutant cancers
- Description
This dataset contains summary data visualizations and clinical data from a broad sampling of HER2- and HER3-mutant tumors. The data was generated utilizing the MSK-IMPACT targeted sequencing test. The clinical data includes tumor type (based on the opensource OncoTree ontology developed at MSK), mutation count, information about mutated genes, Amplification Status, Best objective response rate, Bubble...
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Breast NeoplasmsCarcinoma, HepatocellularCarcinoma, Non-Small-Cell LungCarcinoma, Renal CellColorectal NeoplasmsDNA Mutational AnalysisEndometrial NeoplasmsEsophageal NeoplasmsGenes, erbBGenes, erbB-2MelanomaOvarian NeoplasmsPancreatic NeoplasmsSalivary Gland NeoplasmsSarcomaSkin NeoplasmsUrinary Bladder NeoplasmsUterine Cervical Neoplasms
- Access Rights
- Free to All
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Tumors with TRK fusions (MSK, 2019): Tumors with TRK fusions based on MSK-IMPACT targeted sequencing.
- Description
This dataset contains summary data visualizations and clinical data from a broad sampling of tropomyosin receptor kinase (TRK) fusion tumors. The data was gathered utilizing the MSK-IMPACT targeted sequencing test. The clinical data includes tumor type (based on the opensource OncoTree ontology developed at MSK), information about mutated genes, patient demographics, and modality. The data set also...
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DNA Mutational AnalysisOncogene Proteins, FusionReceptor Protein-Tyrosine KinasesReceptor, trkAReceptor, trkBReceptor, trkC
- Access Rights
- Free to All
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TMB and Immunotherapy (MSKCC, Nat Genet 2019): Genomic and survival data from 1661 tumor-normal pairs from 1661 patients with various cancer types sequenced with the MSK-IMPACT assay.
- Description
This dataset contains summary data visualizations and clinical data from a broad sampling of 1,661 samples of across multiple cancer types showing tumor mutational load and survival following immunotherapy from 1,661 patients. The data was gathered utilizing the MSK-IMPACT targeted sequencing test. The clinical data includes tumor type (based on the opensource OncoTree ontology developed at MSK),...
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DNA Mutational AnalysisImmunotherapyMutationTumor Burden
- Access Rights
- Free to All
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Breast Invasive Carcinoma (TCGA, Firehose Legacy)
- Description
TCGA Breast Invasive Carcinoma. Source data from GDAC Firehose. Previously known as TCGA Provisional. This dataset contains summary data visualizations and clinical data from a broad sampling of 1,108 carcinomas from 1,101 patients. The data was gathered as part of the Broad Institute of MIT and Harvard Firehose initiative, a cancer analysis pipeline. The clinical data includes mutation count, information...
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Breast NeoplasmsCarcinoma, Ductal, BreastCarcinoma, LobularDNA Mutational AnalysisSkin Neoplasms
- Access Rights
- Free to All
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Mixed cfDNA (MSKCC, 2020): IMPACT sequencing of 229 cell-free DNA (cfDNA) and associated tumor samples with matched normal
- Description
This dataset contains the summary data visualizations and clinical data of IMPACT sequencing of 229 cell-free DNA (cfDNA) and associated tumor samples with matched normal from 118 patients. Clinical data includes: Cancer Type, Number of Samples Per Patient, Mutation Count, Fraction Genome Altered, Sex, Primary/Metastasis Sample Type, Collaboration Id, Gene Panel, Oncotree Code, Tumor/cfDNA Sample...
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AdenocarcinomaAdenocarcinoma of LungBreast NeoplasmsCarcinoma, Ductal, BreastCarcinoma, NeuroendocrineCarcinoma, Renal CellCarcinoma, Squamous CellCell-Free Nucleic AcidsChoriocarcinomaEndodermal Sinus TumorMelanomaNeoplasms, Germ Cell and EmbryonalNeoplasms, Squamous CellNeuroendocrine TumorsProstatic NeoplasmsSeminomaSmall Cell Lung CarcinomaUrinary Bladder Neoplasms
- Access Rights
- Free to All
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Breast Cancer (MSK, Cancer Cell 2018): Targeted Sequencing of tumor/normal sample pairs from 1918 Breast cancers.
- Description
This dataset contains the summary data visualizations and clinical data from targeted sequencing of tumor/normal sample pairs from 1,918 Breast cancers from 1,756 patients. Clinical data includes: Cancer Type, Number of Samples Per Patient, Mutation Count, Fraction Genome Altered, Sample Type, Sex, Disease Free (Months), Disease Free Event, ER PCT Primary, ER Status of Sequenced Sample, ER Status...
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Breast Carcinoma In SituBreast NeoplasmsCarcinoma, Adenoid CysticCarcinoma, Ductal, BreastCarcinoma, Lobular
- Access Rights
- Free to All
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Data from: Clonal relatedness between lobular carcinoma in situ and synchronous malignant lesions
- Authors
- Andrade, Victor P.Ostrovnaya, IrinaSeshan, VenkatramanMorrogh, Mary6 more author(s)...
- Description
Summary from Dryad: "Abstract: INTRODUCTION: Lobular carcinoma in situ (LCIS) has been accepted as a marker of risk for the development of invasive breast cancer, yet modern models of breast carcinogenesis include LCIS as a precursor of low-grade carcinomas. We provide evidence favoring a clonal origin for LCIS and synchronous estrogen receptor-positive malignant lesions of the ductal and lobular...
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Biomarkers, TumorCarcinoma, Ductal, BreastCarcinoma, Lobular
- Access Rights
- Free to All