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  • TMB and Immunotherapy (MSKCC, Nat Genet 2019): Genomic and survival data from 1661 tumor-normal pairs from 1661 patients with various cancer types sequenced with the MSK-IMPACT assay.

    Description

    This dataset contains summary data visualizations and clinical data from a broad sampling of 1,661 samples of across multiple cancer types showing tumor mutational load and survival following immunotherapy from 1,661 patients. The data was gathered utilizing the MSK-IMPACT targeted sequencing test. The clinical data includes tumor type (based on the opensource OncoTree ontology developed at MSK),...

    Subject
    DNA Mutational Analysis
    Immunotherapy
    Mutation
    Tumor Burden
    Access Rights
    Free to All
  • SUMMIT - Neratinib Basket Study (Multi-Institute, Nature 2018): MSK-IMPACT sequencing of 86 patients with HER2- and HER3-mutant cancers

    Description

    This dataset contains summary data visualizations and clinical data from a broad sampling of HER2- and HER3-mutant tumors. The data was generated utilizing the MSK-IMPACT targeted sequencing test. The clinical data includes tumor type (based on the opensource OncoTree ontology developed at MSK), mutation count, information about mutated genes, Amplification Status, Best objective response rate, Bubble...

    Subject
    Breast Neoplasms
    Carcinoma, Hepatocellular
    Carcinoma, Non-Small-Cell Lung
    Carcinoma, Renal Cell
    Colorectal Neoplasms
    DNA Mutational Analysis
    Endometrial Neoplasms
    Esophageal Neoplasms
    Genes, erbB
    Genes, erbB-2
    Melanoma
    Ovarian Neoplasms
    Pancreatic Neoplasms
    Salivary Gland Neoplasms
    Sarcoma
    Skin Neoplasms
    Urinary Bladder Neoplasms
    Uterine Cervical Neoplasms
    Access Rights
    Free to All
  • Breast Invasive Carcinoma (TCGA, Firehose Legacy)

    Description

    TCGA Breast Invasive Carcinoma. Source data from GDAC Firehose. Previously known as TCGA Provisional. This dataset contains summary data visualizations and clinical data from a broad sampling of 1,108 carcinomas from 1,101 patients. The data was gathered as part of the Broad Institute of MIT and Harvard Firehose initiative, a cancer analysis pipeline. The clinical data includes mutation count, information...

    Subject
    Breast Neoplasms
    Carcinoma, Ductal, Breast
    Carcinoma, Lobular
    DNA Mutational Analysis
    Skin Neoplasms
    Access Rights
    Free to All
  • Breast Cancer (MSK, Cancer Cell 2018): Targeted Sequencing of tumor/normal sample pairs from 1918 Breast cancers.

    Description

    This dataset contains the summary data visualizations and clinical data from targeted sequencing of tumor/normal sample pairs from 1,918 Breast cancers from 1,756 patients. Clinical data includes: Cancer Type, Number of Samples Per Patient, Mutation Count, Fraction Genome Altered, Sample Type, Sex, Disease Free (Months), Disease Free Event, ER PCT Primary, ER Status of Sequenced Sample, ER Status...

    Subject
    Breast Carcinoma In Situ
    Breast Neoplasms
    Carcinoma, Adenoid Cystic
    Carcinoma, Ductal, Breast
    Carcinoma, Lobular
    Access Rights
    Free to All
  • Breast Cancer (METABRIC, Nature 2012 & Nat Commun 2016)

    Description

    This dataset contains summary data visualizations and clinical data from target sequencing analysis of 2509 primary breast tumors from 2,509 patients. The study was conducted to identify putative cancer genes, revealing novel subgroups with distinct clinical outcomes. The results were validated by long-term clinical follow-up. The clinical data includes mutated genes, 3-gene classifier subtypes, and...

    Subject
    Breast Neoplasms
    Clinical Trial
    Data Visualization
    Sequence Analysis
    Access Rights
    Free to All
  • MSK-CHORD (MSK, Nature 2024)

    Description

    This dataset contains summary data visualizations and clinical data from targeted sequencing of 25040 tumors from 24950 patients and their matched normals via MSK-IMPACT, along with clinical annotations, some of which are derived from natural language processing (denoted NLP). This data is available under the Creative Commons BY-NC-ND 4.0 license. For commercial use, please contact datarequests@mskcc.org....

    Subject
    Clinical Trial
    Data Visualization
    Machine Learning
    Sequence Analysis
    Access Rights
    Free to All