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Lung Adenocarcinoma (TCGA, PanCancer Atlas)
- Description
This dataset contains summary data visualizations and clinical data from a broad sampling of 566 lung adenocarcinomas from 566 patients. The data was gathered as part of the PanCancer Atlas initiative, which aims to answer big, overarching questions about cancer by examining the full set of tumors characterized in the robust TCGA dataset. The clinical data includes mutation count, information about...
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Adenocarcinoma of LungDNA Mutational Analysis
- Access Rights
- Free to All
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MSK-IMPACT Clinical Sequencing Cohort (MSKCC, Nat Med 2017): Targeted sequencing of 10,000 clinical cases using the MSK-IMPACT assay
- Description
This dataset contains summary data visualizations and clinical data from the targeted sequencing of 10,000 clinical cases using the MSK-IMPACT assay. The clinical data includes mutation count, information about mutated genes, tumor mutational burden calculations, tissue site from which the sample was derived, tumor purity among other relevant data points. The data set also includes copy-number segment...
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AdenocarcinomaAdenocarcinoma of LungAdenocarcinoma, MucinousBreast NeoplasmsCarcinoma, Ductal, BreastCarcinoma, HepatocellularCarcinoma, LobularCarcinoma, Non-Small-Cell LungCarcinoma, Renal CellCarcinoma, Squamous CellCarcinosarcomaCholangiocarcinomaColonic NeoplasmsColorectal NeoplasmsCystadenocarcinoma, SerousDNA Mutational AnalysisGallbladder NeoplasmsGlioblastomaLiposarcomaLung NeoplasmsLymphoma, FollicularMelanomaMesotheliomaNeoplasms, Squamous CellNeurofibromaOligodendrogliomaOsteosarcomaOvarian NeoplasmsPancreatic NeoplasmsProstatic NeoplasmsRectal NeoplasmsSarcomaSarcoma, SynovialSquamous Cell Carcinoma of Head and NeckStomach NeoplasmsThyroid Cancer, PapillaryUrinary Bladder NeoplasmsUterine NeoplasmsUveal Neoplasms
- Access Rights
- Free to All
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Thoracic PDX (MSK, Provisional): Targeted sequencing of thoracic PDX lines to characterize genetic alterations in 139 tumor/normal pairs via MSK-IMPACT.
- Description
This dataset contains summary data visualizations and clinical data from a broad 183 samples of thoracic tumors from 77 patients. The data was generated by the Charles Rudin Lab, utilizing the MSK-IMPACT targeted sequencing test. The clinical data includes tumor type (based on the opensource OncoTree ontology developed at MSK), mutation count, information about mutated genes, patient demographics,...
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Adenocarcinoma of LungCarcinoma, Non-Small-Cell LungDNA Mutational AnalysisLung NeoplasmsMesothelioma
- Access Rights
- Free to All
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Lung Adenocarcinoma (TCGA, Firehose Legacy)
- Description
TCGA Lung Adenocarcinoma. Source data from GDAC Firehose. Previously known as TCGA Provisional. This dataset contains summary data visualizations and clinical data from a broad sampling of 586 carcinomas from 584 patients. The data was gathered as part of the Broad Institute of MIT and Harvard Firehose initiative, a cancer analysis pipeline. The clinical data includes mutation count, information about...
- Subject
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Adenocarcinoma of LungDNA Mutational Analysis
- Access Rights
- Free to All
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Mixed cfDNA (MSKCC, 2020): IMPACT sequencing of 229 cell-free DNA (cfDNA) and associated tumor samples with matched normal
- Description
This dataset contains the summary data visualizations and clinical data of IMPACT sequencing of 229 cell-free DNA (cfDNA) and associated tumor samples with matched normal from 118 patients. Clinical data includes: Cancer Type, Number of Samples Per Patient, Mutation Count, Fraction Genome Altered, Sex, Primary/Metastasis Sample Type, Collaboration Id, Gene Panel, Oncotree Code, Tumor/cfDNA Sample...
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AdenocarcinomaAdenocarcinoma of LungBreast NeoplasmsCarcinoma, Ductal, BreastCarcinoma, NeuroendocrineCarcinoma, Renal CellCarcinoma, Squamous CellCell-Free Nucleic AcidsChoriocarcinomaEndodermal Sinus TumorMelanomaNeoplasms, Germ Cell and EmbryonalNeoplasms, Squamous CellNeuroendocrine TumorsProstatic NeoplasmsSeminomaSmall Cell Lung CarcinomaUrinary Bladder Neoplasms
- Access Rights
- Free to All
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Lung Adenocarcinoma (MSKCC, 2020): Targeted sequencing of 604 lung adenocarcinoma tumor/normal pairs via MSK-IMPACT
- Description
This dataset contains the summary data visualizations and clinical data from targeted sequencing of 604 lung adenocarcinoma tumors from 604 patients via MSK-IMPACT. Clinical data includes: Mutation Count, Fraction Genome Altered, Sex, Age At Surgery, Clinical Nodal Status, CT Size, Diffusion lung capacity for carbon monoxide, FEV1, FGA Facets, Overall Survival Status, Pathologic Nodal Status Pathologic...
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AdenocarcinomaAdenocarcinoma of LungLung Neoplasms
- Access Rights
- Free to All
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Non-Small Cell Cancer (MSKCC, Cancer Discov 2017): Targeted sequencing of 860 patients with metastatic lung adenocarcinoma
- Description
This dataset contains the summary data visualizations and clinical data from targeted sequencing of 915 samples from 860 patients with metastatic lung adenocarcinoma. Clinical data includes: Number of Samples Per Patient, Mutation Count, Fraction Genome Altered, Diagnosis Age, Sex, Primary/Metastasis Sample Type, Chemotherapy, Clinical Trial, Driver Mutations, Durable Clinical Benefit, Gene Panel,...
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AdenocarcinomaAdenocarcinoma of LungCarcinoma, Non-Small-Cell LungLung Neoplasms
- Access Rights
- Free to All
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Non-Small Cell Lung Cancer (MSKCC, J Clin Oncol 2018): IMPACT sequencing of 240 NSCLC tumor/normal pairs treated at MSKCC with anti-PD-(L)1 based therapy.
- Description
This dataset contains the summary data visualizations and clinical data from IMPACT sequencing of 240 NSCLC tumor/normal pairs treated at MSKCC with anti-PD-(L)1 based therapy from 240 patients. Clinical data includes: Cancer Type, Mutation Count, Fraction Genome Altered, Sex, Durable Clinical Benefit, FGA, Gene Panel, IRB, Lines of treatment, Mutation Rate, Oncotree Code, PD-L1 Score (%), Smoker,...
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Adenocarcinoma of LungCarcinoma, Large CellCarcinoma, Non-Small-Cell LungCarcinoma, Squamous CellLung Neoplasms
- Access Rights
- Free to All
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A collection of Whole-genome sequencing files from the Cancer Genome Atlas program on Adenocarcinoma, filtered from the GDC Data Portal
- Description
The GDC Data Portal is a robust data-driven platform that allows cancer researchers and bioinformaticians to search and download cancer data for analysis. This dataset is a filtered search result in the GDC Data Portal for TCGA Project, Adenocarcinoma, Whole Genome Sequencing Reads. It consists of 196 BAM files and 99 cases.
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Adenocarcinoma of Lung
- Access Rights
- Application Required
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Characterizing an HSF1-dependent transcriptional program in metastatic lung adenocarcinoma
- Authors
- Hoj, Jacob P.Pendergast, Ann M.
- Description
Summary from the GEO: "The purpose of this study was to identify gene targets differentially regulated by shRNA-mediated knockdown of the HSF1 transcription factor in the brain-metastatic lung adenocarcinoma cell line PC9-BrM3." Overall design from the GEO: "Samples were analyzed for differential gene expression in PC9-BrM3 cells transduced with shRNAs against NTC (non-target control) versus HSF1....
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Adenocarcinoma of LungBrain NeoplasmsHeat Shock Transcription FactorsLung NeoplasmsRNA, Small Interfering
- Access Rights
- Free to All