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Results Found: 8
  • Data from: Clonal relatedness between lobular carcinoma in situ and synchronous malignant lesions

    Authors
    Andrade, Victor P.
    Ostrovnaya, Irina
    Seshan, Venkatraman
    Morrogh, Mary
    6 more author(s)...
    Description

    Summary from Dryad: "Abstract: INTRODUCTION: Lobular carcinoma in situ (LCIS) has been accepted as a marker of risk for the development of invasive breast cancer, yet modern models of breast carcinogenesis include LCIS as a precursor of low-grade carcinomas. We provide evidence favoring a clonal origin for LCIS and synchronous estrogen receptor-positive malignant lesions of the ductal and lobular...

    Subject
    Biomarkers, Tumor
    Carcinoma, Ductal, Breast
    Carcinoma, Lobular
    Access Rights
    Free to All
  • Data from: Reflectance confocal microscopy features of BRAF V600E mutated thin melanomas detected by immunohistochemistry

    Authors
    Urvanegia, Ana Claudia
    Tavoloni Braga, Juliana Casagrande
    Shitara, Danielle
    Fregnani, Jose Humberto
    5 more author(s)...
    Description

    From Dryad summary: "Abstract: The classification of melanoma into four histological subtypes has been questioned regarding its clinical validity in providing relevant information for treatment for metastatic tumors. Specific genetic alterations are associated with particular clinical and histopathological features, suggesting that these could be helpful in refining existing melanoma classification...

    Subject
    Biomarkers, Tumor
    Melanoma
    Melanoma/genetics
    Microscopy, Confocal
    Proto-Oncogene Proteins B-raf
    Access Rights
    Free to All
  • Prostate Adenocarcinoma (MSK, Cancer Cell 2010): Comprehensive profiling of 218 prostate tumors (181 primaries, 37 metastases) and 14 prostate cancer cell lines and xenografts

    Authors
    Taylor, Barry Stephen
    Schultz, Nikolaus D.
    Hieronymus, Haley
    Gopalan, Anuradha
    22 more author(s)...
    Description

    This dataset contains genomic profile samples, mutation information, and sequencing data from 218 prostate tumors, including 181 primaries and 37 metastases, and 14 prostate cancer cell lines and xenografts. After generating a map of CNAs across the dataset, the authors of this study used matching mRNA and microRNA transcriptome and exon resequencing data to define the frequency of alterations in...

    Subject
    Biomarkers, Tumor
    Genomics
    Neoplasm Metastasis
    Prostatic Neoplasms
    Transcriptome
    Access Rights
    Free to All
  • Global proteome analysis of paired colorectal cancer sample using LC-MS/MS

    Authors
    Tanaka, Atsushi
    Roehrl, Michael H.
    Description

    Description from PRIDE: "To find differentially expressed protein in colorectal cancer compared with normal colon tissue, we performed global proteome analysis using LC-MS."

    Subject
    Biomarkers, Tumor
    Colorectal Neoplasms
    Liquid Chromatography-Mass Spectrometry
    Mucous Membrane
    Prolyl Hydroxylases
    Survival Analysis
    Access Rights
    Free to All
  • Colorectal cancer proteome project for biomarke search and development of clinical test

    Authors
    Tanaka, Atsushi
    Roehrl, Michael H.
    Description

    Description from PRIDE: "To find differentially expressed protein in colorectal cancer compared with normal colon tissue, we performed global proteome analysis using LC-MS."

    Subject
    Biomarkers, Tumor
    Colorectal Neoplasms
    Liquid Chromatography-Mass Spectrometry
    Proteome
    Access Rights
    Free to All
  • Copy number alteration burden predicts prostate cancer relapse: Agilent 1M aCGH data for human primary prostate cancer samples

    Authors
    Hieronymus, Haley
    Schultz, Nikolaus D.
    Taylor, Barry Stephen
    Sawyers, Charles L.
    Description

    Summary from GEO: "Prostate cancer is the most common malignancy in men. Yet, the modest benefit of treatment highlights the unmet need for prognostic biomarkers in prostate cancer (1). Few large prostate oncogenome resources currently exist that combine the molecular and clinical outcome data necessary for prognostic discovery. To determine the extent to which genomic aberrations reflect the risk...

    Subject
    Biomarkers, Tumor
    Genomics
    Neoplasm Metastasis
    Prostatic Neoplasms
    Recurrence
    Access Rights
    Free to All
  • Immunometabolic coevolution defines unique microenvironmental niches in ccRCC

    Authors
    Tang, Cerise
    Xie, Amy X.
    Liu, Eric Minwei
    Kuo, Fengshen
    16 more author(s)...
    Description

    Description from Zenodo: "Processed metabolomics and sample data associated with "Immunometabolic coevolution defines unique microenvironmental niches in ccRCC"."

    Subject
    Biomarkers, Tumor
    Metabolomics
    RNA-Seq
    Tumor Microenvironment
    Access Rights
    Free to All
  • CM214 - Biomarker Analysis From the Phase 3 CheckMate 214 Trial of Nivolumab Plus Ipilimumab (N+I) or Sunitinib (S) in Advanced Renal Cell Carcinoma (aRCC)

    Description

    Description from EGA: "CM214 - Biomarker Analysis From the Phase 3 CheckMate 214 Trial of Nivolumab Plus Ipilimumab (N+I) or Sunitinib (S) in Advanced Renal Cell Carcinoma (aRCC)" Anonymized raw FASTQ files of WES and RNA-seq data from 87 patients who granted informed consent to share such data, are made available at the European Genome-Phenome Archive (EGA)

    Subject
    Biomarkers, Tumor
    Carcinoma, Renal Cell
    RNA-Seq
    Access Rights
    Application Required