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Results Found: 35
  • Cryo-EM structure of Csm-crRNA-target RNA ternary bigger complex in complex with cA4 in type III-A CRISPR-Cas system

    Authors
    Jia, Ning
    Patel, Dinshaw J.
    Description

    This deposit in the Research Collaboratory for Structural Bioinformatics Protein Data Base (PDB) includes cryogenic electron microscopy data identifying the structure of Cryo-EM structure of Csm-crRNA-target RNA ternary bigger complex in complex with cA4 in type III-A CRISPR-Cas system. The main summary display for this entry includes an experimental data snapshot, protein source, macromolecules and...

    Subject
    Clustered Regularly Interspaced Short Palindromic Repeats
    CRISPR-Cas Systems
    Cryoelectron Microscopy
    Protein Conformation
    Protein Structure, Quaternary
    Protein Structure, Secondary
    Protein Structure, Tertiary
    Ribonucleases / chemistry
    Access Rights
    Free to All
  • Cryo-EM structure of Csm-crRNA-target RNA ternary complex in complex with cA4 in type III-A CRISPR-Cas system

    Authors
    Jia, Ning
    Patel, Dinshaw J.
    Description

    This deposit in the Research Collaboratory for Structural Bioinformatics Protein Data Base (PDB) includes cryogenic electron microscopy data identifying the structure of Csm-crRNA-target RNA ternary complex in complex with cA4 in type III-A CRISPR-Cas system. The main summary display for this entry includes an experimental data snapshot, protein source, macromolecules and small molecules included...

    Subject
    Clustered Regularly Interspaced Short Palindromic Repeats
    CRISPR-Cas Systems
    Cryoelectron Microscopy
    Protein Conformation
    Protein Structure, Quaternary
    Protein Structure, Secondary
    Protein Structure, Tertiary
    Ribonucleases / chemistry
    Access Rights
    Free to All
  • Cryo-EM structure of Csm-crRNA-target RNA ternary complex in complex with AMPPNP in type III-A CRISPR-Cas system

    Authors
    Jia, Ning
    Patel, Dinshaw J.
    Description

    This deposit in the Research Collaboratory for Structural Bioinformatics Protein Data Base (PDB) includes cryogenic electron microscopy data identifying the structure of Csm-crRNA-target RNA ternary complex in complex with AMPPNP in type III-A CRISPR-Cas system. The main summary display for this entry includes an experimental data snapshot, protein source, macromolecules and small molecules included...

    Subject
    Clustered Regularly Interspaced Short Palindromic Repeats
    CRISPR-Cas Systems
    Cryoelectron Microscopy
    Protein Conformation
    Protein Structure, Quaternary
    Protein Structure, Secondary
    Protein Structure, Tertiary
    Ribonucleases / chemistry
    Access Rights
    Free to All
  • Regulation of the error-prone DNA polymerase polκ by oncogenic signaling and its contribution to drug resistance

    Authors
    Campbell, Nathaniel
    White, Richard Mark
    Description

    Summary from the GEO: "We report how the A375 melanoma cell line changes following CRISPR-Cas9 inactivation of POLK RNA-seq of A375 melanoma cells following CRISPR-Cas9 with either POLK sgRNA or non-targeting control sgRNA (N=3 replicate samples each)." Abstract summary From "Regulation of the error-prone DNA polymerase Polκ by oncogenic signaling and its contribution to drug resistance": "The DNA...

    Subject
    Clustered Regularly Interspaced Short Palindromic Repeats
    CRISPR-Cas Systems
    Melanoma
    Access Rights
    Free to All
  • Cryo-EM structure of Csm-crRNA binary complex in type III-A CRISPR-Cas system

    Authors
    Jia, Ning
    Wang, Chongyuan
    Eng, Edward T.
    Patel, Dinshaw J.
    Description

    This deposit in the Research Collaboratory for Structural Bioinformatics Protein Data Base (PDB) includes cryogenic electron microscopy data identifying the Cryo-EM structure of Csm-crRNA binary complex in type III-A CRISPR-Cas system. The main summary display for this entry includes information on the experimental method, protein source, macromolecules and small molecules included in the deposit,...

    Subject
    CRISPR-Cas Systems
    RNA-Binding Proteins
    Access Rights
    Free to All
  • Cryo-EM structure of ternary Csm-crRNA-target RNA with anti-tag sequence complex in type III-A CRISPR-Cas system

    Authors
    Jia, Ning
    Wang, Chongyuan
    Eng, Edward T.
    Patel, Dinshaw J.
    Description

    This deposit in the Research Collaboratory for Structural Bioinformatics Protein Data Base (PDB) includes cryogenic electron microscopy data identifying the Cryo-EM structure of ternary Csm-crRNA-target RNA with anti-tag sequence complex in type III-A CRISPR-Cas system. The main summary display for this entry includes information on the experimental method, protein source, macromolecules and small...

    Subject
    CRISPR-Cas Systems
    RNA-Binding Proteins
    Access Rights
    Free to All
  • Cryo-EM structure of larger Csm-crRNA-target RNA ternary complex in type III-A CRISPR-Cas system

    Authors
    Jia, Ning
    Wang, Chongyuan
    Eng, Edward T.
    Description

    This deposit in the Research Collaboratory for Structural Bioinformatics Protein Data Base (PDB) includes cryogenic electron microscopy data identifying the Cryo-EM structure of larger Csm-crRNA-target RNA ternary complex in type III-A CRISPR-Cas system. The main summary display for this entry includes information on the experimental method, protein source, macromolecules and small molecules included...

    Subject
    CRISPR-Cas Systems
    RNA-Binding Proteins
    Access Rights
    Free to All
  • Cryo-EM structure of Csm-crRNA-target RNA ternary complex in type III-A CRISPR-Cas system

    Authors
    Jia, Ning
    Wang, Chongyuan
    Eng, Edward T.
    Patel, Dinshaw J.
    Description

    This deposit in the Research Collaboratory for Structural Bioinformatics Protein Data Base (PDB) includes cryogenic electron microscopy data identifying the Cryo-EM structure of Csm-crRNA-target RNA ternary complex in type III-A CRISPR-Cas system. The main summary display for this entry includes information on the experimental method, protein source, macromolecules and small molecules included in...

    Subject
    CRISPR-Cas Systems
    RNA-Binding Proteins
    Access Rights
    Free to All
  • Crystal structure of Csm1-Csm4 subcomplex in the type III-A CRISPR-Csm interference complex

    Authors
    Jia, Ning
    Patel, Dinshaw J.
    Description

    This deposit in the Research Collaboratory for Structural Bioinformatics Protein Data Base (PDB) includes cryogenic electron microscopy data identifying the Crystal structure of Csm1-Csm4 subcomplex in the type III-A CRISPR-Csm interference complex. The main summary display for this entry includes information on the experimental method, protein source, macromolecules and small molecules included in...

    Subject
    CRISPR-Cas Systems
    RNA-Binding Proteins
    Access Rights
    Free to All
  • Cryo-EM structure of Cas13(crRNA)

    Authors
    Jia, Ning
    Meeske, Alexander J.
    Marraffini, Luciano A.
    Patel, Dinshaw J.
    Description

    This deposit in the Research Collaboratory for Structural Bioinformatics Protein Data Base (PDB) includes electron microscopy data used for modeling the Cryo-EM structure of Cas13(crRNA). The main summary display for this entry includes information on the experimental data, validation, macromolecules and version history. Data is provided for download as FASTA sequence format, the Protein Data Bases...

    Subject
    Clustered Regularly Interspaced Short Palindromic Repeats
    CRISPR-Associated Proteins
    CRISPR-Cas Systems
    DNA-Directed RNA Polymerases
    Listeria
    Access Rights
    Free to All