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Cryo-EM structure of Csm-crRNA-target RNA ternary bigger complex in complex with cA4 in type III-A CRISPR-Cas system
- Authors
- Jia, NingPatel, Dinshaw J.
- Description
This deposit in the Research Collaboratory for Structural Bioinformatics Protein Data Base (PDB) includes cryogenic electron microscopy data identifying the structure of Cryo-EM structure of Csm-crRNA-target RNA ternary bigger complex in complex with cA4 in type III-A CRISPR-Cas system. The main summary display for this entry includes an experimental data snapshot, protein source, macromolecules and...
- Subject
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Clustered Regularly Interspaced Short Palindromic RepeatsCRISPR-Cas SystemsCryoelectron MicroscopyProtein ConformationProtein Structure, QuaternaryProtein Structure, SecondaryProtein Structure, TertiaryRibonucleases / chemistry
- Access Rights
- Free to All
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Cryo-EM structure of Csm-crRNA-target RNA ternary complex in complex with cA4 in type III-A CRISPR-Cas system
- Authors
- Jia, NingPatel, Dinshaw J.
- Description
This deposit in the Research Collaboratory for Structural Bioinformatics Protein Data Base (PDB) includes cryogenic electron microscopy data identifying the structure of Csm-crRNA-target RNA ternary complex in complex with cA4 in type III-A CRISPR-Cas system. The main summary display for this entry includes an experimental data snapshot, protein source, macromolecules and small molecules included...
- Subject
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Clustered Regularly Interspaced Short Palindromic RepeatsCRISPR-Cas SystemsCryoelectron MicroscopyProtein ConformationProtein Structure, QuaternaryProtein Structure, SecondaryProtein Structure, TertiaryRibonucleases / chemistry
- Access Rights
- Free to All
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Cryo-EM structure of Csm-crRNA-target RNA ternary complex in complex with AMPPNP in type III-A CRISPR-Cas system
- Authors
- Jia, NingPatel, Dinshaw J.
- Description
This deposit in the Research Collaboratory for Structural Bioinformatics Protein Data Base (PDB) includes cryogenic electron microscopy data identifying the structure of Csm-crRNA-target RNA ternary complex in complex with AMPPNP in type III-A CRISPR-Cas system. The main summary display for this entry includes an experimental data snapshot, protein source, macromolecules and small molecules included...
- Subject
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Clustered Regularly Interspaced Short Palindromic RepeatsCRISPR-Cas SystemsCryoelectron MicroscopyProtein ConformationProtein Structure, QuaternaryProtein Structure, SecondaryProtein Structure, TertiaryRibonucleases / chemistry
- Access Rights
- Free to All
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Regulation of the error-prone DNA polymerase polκ by oncogenic signaling and its contribution to drug resistance
- Authors
- Campbell, NathanielWhite, Richard Mark
- Description
Summary from the GEO: "We report how the A375 melanoma cell line changes following CRISPR-Cas9 inactivation of POLK RNA-seq of A375 melanoma cells following CRISPR-Cas9 with either POLK sgRNA or non-targeting control sgRNA (N=3 replicate samples each)." Abstract summary From "Regulation of the error-prone DNA polymerase Polκ by oncogenic signaling and its contribution to drug resistance": "The DNA...
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Clustered Regularly Interspaced Short Palindromic RepeatsCRISPR-Cas SystemsMelanoma
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- Free to All
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Cryo-EM structure of Csm-crRNA binary complex in type III-A CRISPR-Cas system
- Authors
- Jia, NingWang, ChongyuanEng, Edward T.Patel, Dinshaw J.
- Description
This deposit in the Research Collaboratory for Structural Bioinformatics Protein Data Base (PDB) includes cryogenic electron microscopy data identifying the Cryo-EM structure of Csm-crRNA binary complex in type III-A CRISPR-Cas system. The main summary display for this entry includes information on the experimental method, protein source, macromolecules and small molecules included in the deposit,...
- Subject
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CRISPR-Cas SystemsRNA-Binding Proteins
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- Free to All
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Cryo-EM structure of ternary Csm-crRNA-target RNA with anti-tag sequence complex in type III-A CRISPR-Cas system
- Authors
- Jia, NingWang, ChongyuanEng, Edward T.Patel, Dinshaw J.
- Description
This deposit in the Research Collaboratory for Structural Bioinformatics Protein Data Base (PDB) includes cryogenic electron microscopy data identifying the Cryo-EM structure of ternary Csm-crRNA-target RNA with anti-tag sequence complex in type III-A CRISPR-Cas system. The main summary display for this entry includes information on the experimental method, protein source, macromolecules and small...
- Subject
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CRISPR-Cas SystemsRNA-Binding Proteins
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- Free to All
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Cryo-EM structure of larger Csm-crRNA-target RNA ternary complex in type III-A CRISPR-Cas system
- Authors
- Jia, NingWang, ChongyuanEng, Edward T.
- Description
This deposit in the Research Collaboratory for Structural Bioinformatics Protein Data Base (PDB) includes cryogenic electron microscopy data identifying the Cryo-EM structure of larger Csm-crRNA-target RNA ternary complex in type III-A CRISPR-Cas system. The main summary display for this entry includes information on the experimental method, protein source, macromolecules and small molecules included...
- Subject
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CRISPR-Cas SystemsRNA-Binding Proteins
- Access Rights
- Free to All
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Cryo-EM structure of Csm-crRNA-target RNA ternary complex in type III-A CRISPR-Cas system
- Authors
- Jia, NingWang, ChongyuanEng, Edward T.Patel, Dinshaw J.
- Description
This deposit in the Research Collaboratory for Structural Bioinformatics Protein Data Base (PDB) includes cryogenic electron microscopy data identifying the Cryo-EM structure of Csm-crRNA-target RNA ternary complex in type III-A CRISPR-Cas system. The main summary display for this entry includes information on the experimental method, protein source, macromolecules and small molecules included in...
- Subject
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CRISPR-Cas SystemsRNA-Binding Proteins
- Access Rights
- Free to All
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Crystal structure of Csm1-Csm4 subcomplex in the type III-A CRISPR-Csm interference complex
- Authors
- Jia, NingPatel, Dinshaw J.
- Description
This deposit in the Research Collaboratory for Structural Bioinformatics Protein Data Base (PDB) includes cryogenic electron microscopy data identifying the Crystal structure of Csm1-Csm4 subcomplex in the type III-A CRISPR-Csm interference complex. The main summary display for this entry includes information on the experimental method, protein source, macromolecules and small molecules included in...
- Subject
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CRISPR-Cas SystemsRNA-Binding Proteins
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- Free to All
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Cryo-EM structure of Cas13(crRNA)
- Authors
- Jia, NingMeeske, Alexander J.Marraffini, Luciano A.Patel, Dinshaw J.
- Description
This deposit in the Research Collaboratory for Structural Bioinformatics Protein Data Base (PDB) includes electron microscopy data used for modeling the Cryo-EM structure of Cas13(crRNA). The main summary display for this entry includes information on the experimental data, validation, macromolecules and version history. Data is provided for download as FASTA sequence format, the Protein Data Bases...
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Clustered Regularly Interspaced Short Palindromic RepeatsCRISPR-Associated ProteinsCRISPR-Cas SystemsDNA-Directed RNA PolymerasesListeria
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- Free to All