Comparison of WT and GLIS3-/- cells at various stages of human pancreatic differentiation. From Gene Expression Omnibus authors' summary: "Through development and use of a minimal component protocol for derivation of late stage pancreatic progenitors and beta-like cells, we compared WT and GLIS3-/- pancreatic cells at different stages and discovered that GLIS3-/- cells show an ectopic activation...

Summary from GitHub: This repository contains the R scripts necessary to perform the analysis in our paper Tang, Xuming et al. “SARS-CoV-2 Infection Induces Beta Cell Transdifferentiation.” Cell Metabolism, 19 May. 2021, doi:10.1016/j.cmet.2021.05.015, as described in the supplementary methods and main text." Input data: "The single cell RNA-seq data were generated with the 10X Chromium and pre-processed...

Summary from GEO: "CD8 T cells specific for beta cell antigen islet-specific glucose-6-phosphatase catalytic subunit-related protein (IGRP) were identified and isolated with NRP-V7 tetramers from the pancreatic draining lymph node and pancreas of non-obese diabetic (NOD) mice and used for single-cell RNA-seq and VDJ-seq." Overall design from GEO: "Activated CD8+NRP-V7+ T cells were sorted from...