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Data from: Forward genetic screen of human transposase genomic rearrangements
- Authors
- Henssen, Anton G.Jiang, EileenZhuang, JialiPinello, Luca8 more author(s)...
- Description
Summary from Dryad: "Abstract: Background: Numerous human genes encode potentially active DNA transposases or recombinases, but our understanding of their functions remains limited due to shortage of methods to profile their activities on endogenous genomic substrates. Results: To enable functional analysis of human transposase-derived genes, we combined forward chemical genetic hypoxanthine-guanine...
- Subject
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Genetic TestingGenomicsSequence Analysis, DNATransposases
- Access Rights
- Free to All
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Supplemental materials for Jung et al, 2019
- Authors
- Jung, Hea-JinLittmann, Eric R.Seok, RuthLeiner, Ingrid M.7 more author(s)...
- Description
Description from Figshare: "Table S1. List of MH258 chromosomal essential genes as identified by the EL-ARTIST pipeline (19). For the sliding window analysis, 1000 simulations, window size of 10, and p-value of 0.05 were used. 1, non-essential; 2, essential; 3, domain essential. Table S2. Mutants with enhanced fitness in gut colonization. Ratios of the read counts to the total read counts are listed...
- Subject
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Genetic LociGenetic TestingMutation/geneticsProteomics
- Access Rights
- Free to All