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  • Effects of Ars2 or DGCR8 siRNA on microRNA expression

    Authors
    Olejniczak, Scott Henry
    Gruber, Joshua
    Dreyfuss, Gideon
    Thompson, Craig B.
    Description

    Summary from GEO: "Ars2 is a component of the nuclear cap-binding complex that is required for cellular proliferation and contributes to microRNA biogenesis. Arrays were performed to determine the repertoire of microRNAs that change following knock-down of Ars2. Knock-down of DGCR8 was also performed to determine which microRNAs were expressed and had half-lives short enough to significantly decrease...

    Subject
    Gene Expression
    Gene Knockdown Techniques
    HeLa Cells
    MicroRNAs
    RNA-Binding Proteins
    Access Rights
    Free to All
  • Effects of Ars2 or DGCR8 siRNA on gene expression

    Authors
    Olejniczak, Scott Henry
    Gruber, Joshua
    Dreyfuss, Gideon
    Thompson, Craig B.
    Description

    Summary from GEO: "Ars2 is a component of the nuclear cap-binding complex that is required for cellular proliferation and contributes to microRNA biogenesis. Arrays were performed to determine the repertoire of genes that change following knock-down of Ars2. Knock-down of DGCR8 was also performed to determine which changes in Ars2 knock-down cells resulted from defects in microRNA expression."...

    Subject
    Gene Expression
    Gene Knockdown Techniques
    HeLa Cells
    MicroRNAs
    RNA-Binding Proteins
    Access Rights
    Free to All