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Table S6 from Phase II Clinical Trial of Everolimus in a Pan-Cancer Cohort of Patients with mTOR Pathway Alterations
- Authors
- Adib, ElioKlonowska, KatarzynaGiannikou, KrinioDo, Khanh T.15 more author(s)...
- Description
Description from Figshare: "Table S6. Copy number alterations (CNAs) in cancer genes identified by whole exome sequencing (WES) and/or initial panel sequencing. Each sheet is a different tumor sample."
- Subject
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Clinical Trial, Phase IIDNA Copy Number VariationsEverolimusHigh-Throughput Nucleotide SequencingNeoplasms/drug therapyTOR Serine-Threonine Kinases
- Access Rights
- Free to All
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Table S1 from Phase II Clinical Trial of Everolimus in a Pan-Cancer Cohort of Patients with mTOR Pathway Alterations
- Authors
- Adib, ElioKlonowska, KatarzynaGiannikou, KrinioDo, Khanh T.15 more author(s)...
- Description
Description from Figshare: "Table S1. Massively Parallel Sequencing (MPS) metrics and cancer sample characteristics."
- Subject
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Clinical Trial, Phase IIEverolimusHigh-Throughput Nucleotide SequencingNeoplasms/drug therapyTOR Serine-Threonine Kinases
- Access Rights
- Free to All
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Supplementary Table 1 from Next-Generation Sequencing of Pulmonary Large Cell Neuroendocrine Carcinoma Reveals Small Cell Carcinoma–like and Non–Small Cell Carcinoma–like Subsets
- Authors
- Rekhtman, NatashaPietanza, Maria C.Hellmann, Matthew D.Naidoo, Jarushka16 more author(s)...
- Description
Description from Figshare: "Supplementary Table 1: Next-generation sequencing (MSK-IMPACT) gene panel"
- Subject
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Carcinoma, NeuroendocrineCarcinoma, Non-Small-Cell LungHigh-Throughput Nucleotide SequencingLung NeoplasmsSmall Cell Lung Carcinoma
- Access Rights
- Free to All
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Replication-coupled nucleosome assembly and positioning by ATP-dependent chromatin remodeling enzymes
- Authors
- Yadav, TejasWhitehouse, Iestyn
- Description
Summary from GEO: "We have previously shown that Okazaki fragments in Saccharomyces cerevisiae are sized according to the chromatin repeat. Here we demonstrate that nucleosome positioning is rapidly established on newly synthesized DNA. Using deep sequencing, we demonstrate that ATP-dependent chromatin remodeling enzymes, Isw1 and Chd1, collaborate with histone chaperones, such as CAF-1 and Rtt106,...
- Subject
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ChromatinDNA Ligase ATPDNA ReplicationHigh-Throughput Nucleotide SequencingNucleosomes
- Access Rights
- Free to All
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CRISPR enhancer scan to detect critical elements for the regulation of EVI1 in a translocated enhancer
- Authors
- Delwel, Ruud
- Description
Description from EMBL-EBI: "To uncover, in an unbiased fashion, which elements of the 18 kb translocated region control EVI1 transcription, we devised a CRISPR/Cas9-based enhancer scanning approach. We considered all possible sgRNA target sites containing a canonical Cas9 PAM site (NGG) on both strands of the minimal 18 kb translocated region. Deep-sequencing libraries were generated by PCR amplification...
- Subject
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CRISPR-Cas SystemsHigh-Throughput Nucleotide SequencingLeukemiaMDS1 and EVI1 Complex Locus ProteinPolymerase Chain Reaction
- Access Rights
- Free to All