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Results Found: 8
  • Table S6 from Phase II Clinical Trial of Everolimus in a Pan-Cancer Cohort of Patients with mTOR Pathway Alterations

    Authors
    Adib, Elio
    Klonowska, Katarzyna
    Giannikou, Krinio
    Do, Khanh T.
    15 more author(s)...
    Description

    Description from Figshare: "Table S6. Copy number alterations (CNAs) in cancer genes identified by whole exome sequencing (WES) and/or initial panel sequencing. Each sheet is a different tumor sample."

    Subject
    Clinical Trial, Phase II
    DNA Copy Number Variations
    Everolimus
    High-Throughput Nucleotide Sequencing
    Neoplasms/drug therapy
    TOR Serine-Threonine Kinases
    Access Rights
    Free to All
  • Table S1 from Phase II Clinical Trial of Everolimus in a Pan-Cancer Cohort of Patients with mTOR Pathway Alterations

    Authors
    Adib, Elio
    Klonowska, Katarzyna
    Giannikou, Krinio
    Do, Khanh T.
    15 more author(s)...
    Description

    Description from Figshare: "Table S1. Massively Parallel Sequencing (MPS) metrics and cancer sample characteristics."

    Subject
    Clinical Trial, Phase II
    Everolimus
    High-Throughput Nucleotide Sequencing
    Neoplasms/drug therapy
    TOR Serine-Threonine Kinases
    Access Rights
    Free to All
  • Supplementary Table 1 from Next-Generation Sequencing of Pulmonary Large Cell Neuroendocrine Carcinoma Reveals Small Cell Carcinoma–like and Non–Small Cell Carcinoma–like Subsets

    Authors
    Rekhtman, Natasha
    Pietanza, Maria C.
    Hellmann, Matthew D.
    Naidoo, Jarushka
    16 more author(s)...
    Description

    Description from Figshare: "Supplementary Table 1: Next-generation sequencing (MSK-IMPACT) gene panel"

    Subject
    Carcinoma, Neuroendocrine
    Carcinoma, Non-Small-Cell Lung
    High-Throughput Nucleotide Sequencing
    Lung Neoplasms
    Small Cell Lung Carcinoma
    Access Rights
    Free to All
  • Replication-coupled nucleosome assembly and positioning by ATP-dependent chromatin remodeling enzymes

    Authors
    Yadav, Tejas
    Whitehouse, Iestyn
    Description

    Summary from GEO: "We have previously shown that Okazaki fragments in Saccharomyces cerevisiae are sized according to the chromatin repeat. Here we demonstrate that nucleosome positioning is rapidly established on newly synthesized DNA. Using deep sequencing, we demonstrate that ATP-dependent chromatin remodeling enzymes, Isw1 and Chd1, collaborate with histone chaperones, such as CAF-1 and Rtt106,...

    Subject
    Chromatin
    DNA Ligase ATP
    DNA Replication
    High-Throughput Nucleotide Sequencing
    Nucleosomes
    Access Rights
    Free to All
  • CRISPR enhancer scan to detect critical elements for the regulation of EVI1 in a translocated enhancer

    Authors
    Delwel, Ruud
    Description

    Description from EMBL-EBI: "To uncover, in an unbiased fashion, which elements of the 18 kb translocated region control EVI1 transcription, we devised a CRISPR/Cas9-based enhancer scanning approach. We considered all possible sgRNA target sites containing a canonical Cas9 PAM site (NGG) on both strands of the minimal 18 kb translocated region. Deep-sequencing libraries were generated by PCR amplification...

    Subject
    CRISPR-Cas Systems
    High-Throughput Nucleotide Sequencing
    Leukemia
    MDS1 and EVI1 Complex Locus Protein
    Polymerase Chain Reaction
    Access Rights
    Free to All
  • Picard Toolkit

    Description

    Description from GitHub: "A set of Java command line tools for manipulating high-throughput sequencing (HTS) data and formats. Picard is implemented using the HTSJDK Java library HTSJDK to support accessing file formats that are commonly used for high-throughput sequencing data such as SAM and VCF. As of version 3.0, Picard requires Java 1.17."

    Subject
    Data Analysis
    Electronic Data Processing
    High-Throughput Nucleotide Sequencing
    Metadata
    Access Rights
    Free to All
  • AscatNGS

    Authors
    Raine, Keiran
    Menzies, Andy
    Alcantara, Raul
    Beal, Simon
    Description

    Description from GitHub: "AscatNGS contains the Cancer Genome Projects workflow implementation of the ASCAT copy number algorithm for paired end sequencing. We do not offer support for WXS analysis, please contact the authors of ASCAT here. For details of the underlying algorithm please see the ASCAT site. "

    Subject
    Algorithms
    Data Analysis
    DNA Copy Number Variations
    High-Throughput Nucleotide Sequencing
    Access Rights
    Free to All
  • cgpBattenberg

    Authors
    Raine, Keiran
    Beal, Kathryn
    Dentro, Stefan
    Chapman, Brad
    1 more author(s)...
    Description

    Description from GitHub: "An installation helper, perl wrapper and the R program Battenberg which detects subclonality and copy number in matched NGS data."

    Subject
    Data Analysis
    DNA Copy Number Variations
    Electronic Data Processing
    High-Throughput Nucleotide Sequencing
    Access Rights
    Free to All