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Supplementary Tables from Selective Inhibition of HDAC3 Targets Synthetic Vulnerabilities and Activates Immune Surveillance in Lymphoma
- Authors
- Mondello, PatriziaTadros, SaberTeater, MattFontan, Lorena25 more author(s)...
- Description
13 supplementary tables supporting "Selective Inhibition of HDAC3 Targets Synthetic Vulnerabilities and Activates Immune Surveillance in Lymphoma." The contents of the tables are as follows: Table S1: Differential H3K27Ac in CREBBP-WT vs CREBBP-R1446C Table S2: Differentially expressed genes in CREBBP-WT vs CREBBP-R1446C Table S3: Hypergeometric gene set enrichment analysis of differential H3K27Ac...
- Subject
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Gene ExpressionHistone AcetyltransferasesLymphoma, B-CellMutation/genetics
- Access Rights
- Free to All
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Selective inhibition of HDAC3 targets synthetic vulnerabilities and activates immune surveillance in lymphoma
- Authors
- Mondello, PatriziaTeater, MattMelnick, Ari M.Green, Michael R.
- Description
Summary from GEO: "CREBBP mutations are highly recurrent in B-cell lymphomas and either inactivate its histone acetyltransferase (HAT) domain or truncate the protein. Herein, we show that these two classes of mutations yield different degrees of disruption of the epigenome, with HAT mutations being more severe and associated with inferior clinical outcome. Genes perturbed by CREBBP mutation are direct...
- Subject
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Histone AcetyltransferasesLymphoma, B-CellMutation/geneticsRNA, Guide, CRISPR-Cas Systems
- Access Rights
- Free to All
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Supplemental Table S2 from Histone Acetyltransferase Activity of MOF Is Required for MLL-AF9 Leukemogenesis
- Authors
- Valerio, Daria G.Xu, HaimingChen, Chun-WeiHoshii, Takayuki11 more author(s)...
- Description
Description from Figshare: "RNA-seq MOF KO vs MOF WT"
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Gene Knockout TechniquesHistone AcetyltransferasesLeukemiaRNA-Seq
- Access Rights
- Free to All
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Supplemental table S1 from Histone Acetyltransferase Activity of MOF Is Required for MLL-AF9 Leukemogenesis
- Authors
- Valerio, Daria G.Xu, HaimingChen, Chun-WeiHoshii, Takayuki11 more author(s)...
- Description
Description from Figshare: "RNAi screen data summary"
- Subject
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Histone AcetyltransferasesLeukemiaRNA Interference
- Access Rights
- Free to All