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Discovery of a Drug Candidate for GLIS3-Associated Diabetes
- Authors
- Amin, SadafCook, BrandochZhou, TingGhazizadeh, Zaniar13 more author(s)...
- Description
Comparison of WT and GLIS3-/- cells at various stages of human pancreatic differentiation. From Gene Expression Omnibus authors' summary: "Through development and use of a minimal component protocol for derivation of late stage pancreatic progenitors and beta-like cells, we compared WT and GLIS3-/- pancreatic cells at different stages and discovered that GLIS3-/- cells show an ectopic activation...
- Subject
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Cell Differentiation/geneticsDiabetes MellitusHuman Embryonic Stem CellsHypoglycemic AgentsInsulin-Secreting CellsTranscription Factors
- Access Rights
- Free to All
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Directed differentiation of oligodendrocytes from human embryonic stem cells
- Authors
- Major, TamaraTabar, Viviane S
- Description
Summary from GEO: "Here we compare the transcriptional profile of the undifferentiated hESC with the anterior oligodendroctes derived from the hESC using our new differentiation protocol." Overall design from GEO: "Total RNA was isolated from undifferentiated hES cells and from hES derived oligodendrocytes, 70 days old and FACS sorted for O4 marker. Samples for each group in triplicate were...
- Subject
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Cell DifferentiationGenomicsHuman Embryonic Stem CellsOligodendroglia
- Access Rights
- Free to All