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MeRIP-seq mapping of m6A in the IFN-β induced transcriptome in Huh7 cells
- Authors
- McFadden, Michael J.McIntyre, Alexa B RGokhale, Nandan S.Mason, Christopher E1 more author(s)...
- Description
Summary from the GEO: "The RNA modification N6-methyladenosine (m6A) regulates gene expression through various transcript-specific effects. The goal of this experiment was to identify m6A-modified transcripts during the type I interferon response, with interest in determining which interferon-stimulated genes are modified by m6A. We found that a high percentage of ISGs are m6A-modified, and in follow-up...
- Subject
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Gene ExpressionInterferon Type IInterferonsTranscription Factors
- Access Rights
- Free to All
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Genetic ancestry effects on the response to viral infection are pervasive but cell type specific
- Authors
- Randolph, Haley E.
- Description
Description from BioProject: "Humans differ in their susceptibility to infectious disease, partly due to variation in the immune response following infection. We used single-cell RNA-sequencing to quantify variation in the response to influenza infection in peripheral blood mononuclear cells from European- and African-ancestry males. Genetic ancestry effects are common but highly cell type-specific....
- Subject
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Immunity, ActiveInfluenza, HumanInterferon Type ISingle-Cell Gene Expression AnalysisViral Infections
- Access Rights
- Free to All