This deposit in the Research Collaboratory for Structural Bioinformatics Protein Data Base (PDB) includes cryogenic electron microscopy data identifying the Cryo-EM structure of AcrVIA1-Cas13(crRNA) complex. The main summary display for this entry includes information on the experimental method and validation, macromolecules and version history. Data is provided for download as FASTA sequence format,...

This deposit in the Research Collaboratory for Structural Bioinformatics Protein Data Base (PDB) includes electron microscopy data used for modeling the Cryo-EM structure of Cas13(crRNA). The main summary display for this entry includes information on the experimental data, validation, macromolecules and version history. Data is provided for download as FASTA sequence format, the Protein Data Bases...

BioProject description: "Genome sequencing of Listeria seeligeri LS46 and LS59". The whole genome sequencing of these listeriaphage enabled researchers to discover that AcrVIA1, an anti-CRISPR protein, interacts with the guide-exposed face of Cas13a, a (crRNA)-guided nuclease, preventing access to the target RNA and the conformational changes required for nuclease activation. A single dose of AcrVIA1...