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  • Cryo-EM structure of the Caspase-1-CARD:ASC-CARD octamer

    Authors
    Hollingsworth, Louis R.
    David, Liron
    Li, Yang
    Ruan, Jianbin
    1 more author(s)...
    Description

    This deposit in the Research Collaboratory for Structural Bioinformatics Protein Data Base (PDB) includes cryogenic electron microscopy data identifying the cryo-EM structure of CARD8-CARD filament. The main summary display for this entry includes information on the experimental method, validation and macromolecules in the deposit, as well as entry history and funding information. Data is provided...

    Subject
    Adaptor Proteins, Signal Transducing
    Amino Acid Transport System ASC
    Ankyrins
    Apoptosis
    Caspase 1
    Caspase Activation and Recruitment Domain
    Death Domain Receptor Signaling Adaptor Proteins
    Inflammasomes
    Neoplasm Proteins
    NLR Family, Pyrin Domain-Containing 3 Protein
    NLR Proteins
    Access Rights
    Free to All
  • Cryo-EM structure of the NLRP1-CARD filament

    Authors
    Hollingsworth, Louis R.
    David, Liron
    Li, Yang
    Sharif, Humayun
    3 more author(s)...
    Description

    This deposit in the Research Collaboratory for Structural Bioinformatics Protein Data Base (PDB) includes cryogenic electron microscopy data identifying the cryo-EM structure of the NLRP1-CARD filament. The main summary display for this entry includes information on the experimental method, validation and macromolecules in the deposit, as well as entry history and funding information. Data is provided...

    Subject
    Adaptor Proteins, Signal Transducing
    Ankyrins
    Apoptosis
    Apoptosis Regulatory Proteins
    CARD Signaling Adaptor Proteins
    Caspase 1
    Caspase Activation and Recruitment Domain
    Death Domain Receptor Signaling Adaptor Proteins
    Inflammasomes
    Neoplasm Proteins
    NLR Proteins
    Access Rights
    Free to All
  • Hao Wu Lab OSF figures and Pymol/chimera session files

    Authors
    Hollingsworth, Louis R.
    Xia, Shiyu
    Sharif, Humayun
    David, Liron
    5 more author(s)...
    Description

    Open Science Framework (OSF) is a repository with tools for data discovery, collection, storage and analysis, as well as study experiment design and publication. The Hao Wu Lab files are organized according to the publication they support. Available files include figures used in publications, PyMOL (.pse) and Chimera (.csx) session files which generate the 3D display of biological molecules and .pdb...

    Subject
    CARD Signaling Adaptor Proteins
    Caspase Activation and Recruitment Domain
    Inflammasomes
    NLR Proteins
    Access Rights
    Free to All