-
Pan-Cancer Atlas (PanCanAtlas)
- Description
The Pan-Cancer Atlas (PanCanAtlas) initiative aims to answer big, overarching questions about cancer by examining the full set of tumors characterized in the robust TCGA dataset. The Cancer Genome Atlas (TCGA) Research Network has profiled and analyzed large numbers of human tumors to discover molecular aberrations at the DNA, RNA, protein and epigenetic levels. The resulting rich data provide a major...
- Subject
-
Gene Expression ProfilingNeoplasms/geneticsOncogenesSignal Transduction
- Access Rights
- Free to AllFree to all with registration
-
Oncogenic KRAS(G12V) and BRAF(V600E) in intestinal organoids
- Authors
- Riemer, PamelaMorkel, Marcus
- Description
Summary from GEO: "Goals of the study was to compare transcripional and phenotypic response of mouse intestinal organoid cultures to the KRAS(G12V) or BRAF(V600E)oncogenes." Overall design from GEO: "Two biological replicates of organoids with transgenic luc-tdTomato, KRAS(G12V)-tdTomato, BRAF(V600E)-tdTomato were analysed by RNA-Seq. By comparing 7-10 x 10E7 50bp paired end reads per library...
- Subject
-
Epithelial CellsGenes, rasOncogenesProto-Oncogene Proteins B-rafRNA-Seq
- Access Rights
- Free to All