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TMEM41B is a pan-flavivirus host factor
- Authors
- Hoffmann, H.-HeinrichSchneider, William M.Rozen-Gagnon, KathrynMiles, Linde A.10 more author(s)...
- Description
Summary from the GEO: "Flaviviruses pose a constant threat to human health. These RNA viruses are transmitted by the bite of infected mosquitoes and ticks and regularly cause outbreaks. To identify host factors required for flavivirus infection we performed full-genome loss of function CRISPR-Cas9 screens. Based on these results we focused our efforts on characterizing the roles that TMEM41B and VMP1...
- Subject
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CRISPR-Cas SystemsFlavivirusFlavivirus InfectionsMembrane ProteinsPolymorphism, Single NucleotideVirus Replication
- Access Rights
- Free to All
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Genome-wide association study for Bladder Cancer Risk
- Authors
- Rothman, NathanielGarcia-Closas, MontserratSilverman, DebraChanock, Stephen18 more author(s)...
- Description
Description from dbGaP: "This study funded by the National Cancer Institute (NCI) involves conducting a genome-wide association study of common genetic variants to identify markers of susceptibility to bladder cancer. This bladder GWAS has led to the discovery of three novel regions in the genome associated with bladder cancer risk. Cases were defined as individuals having histologically confirmed...
- Subject
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Genome-Wide Association StudyGenomicsNeoplasms/geneticsPolymorphism, Single NucleotideUrinary Bladder Neoplasms
- Access Rights
- Application Required