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Results Found: 3
  • MaTAR25 lncRNA regulates the Tensin1 gene to impact breast cancer progression

    Authors
    Chang, Kung-Chi
    Diermeier, Sarah D
    Spector, David L.
    Description

    Summary from the GEO: "Misregulation of long non-coding RNA genes has been linked to a wide variety of cancer types. Here we report on Mammary Tumor Associated RNA 25 (MaTAR25), a nuclear enriched and chromatin associated lncRNA that plays a role in mammary tumor cell proliferation, migration, and invasion, both in vitro and in vivo. MaTAR25 functions by interacting with purine rich element binding...

    Subject
    Breast Neoplasms
    DNA-Binding Proteins
    RNA, Long Noncoding
    Tensins
    Access Rights
    Free to All
  • MaTAR25 RNA Antisense Pulldown and Mass Spectrometry

    Authors
    Chang, Kung-Chi
    Spector, David L.
    Description

    Description from PRIDE: "It has been suggested that lncRNAs can interact with transcriptional regulators/co-factors to form ribonucleoprotein (RNP) complexes to regulate the expression of downstream genes in the cell nucleus. To identify potential interacting proteins of MaTAR25, we used two different paired sets of biotin-labeled antisense oligonucleotides targeting MaTAR25 for native RNA antisense...

    Subject
    Breast Neoplasms
    RNA, Antisense
    RNA, Long Noncoding
    Access Rights
    Free to All
  • Genome Reference Consortium Human Build 38 patch release 13 (GRCh38.p13)

    Description

    This record corresponds to the Human Genome data from the Genome Reference Consortium's build 38 patch release 13, published in 2013. It includes GTF / GFF3 files with comprehensive gene annotation, basic gene annotation, long non-coding RNA gene annotation, PolyA feature annotation, consensus pseudogenes predicted by the Yale and UCSC pipelines, predicted tRNA genes; FASTA files with transcript sequences,...

    Subject
    Genomics
    RNA, Long Noncoding
    Transcription, Genetic
    Whole Genome Sequencing
    Access Rights
    Free to All