Summary from GEO: "The eIF4E translation initiation factor has oncogenic properties and concordantly, the inhibitory eIF4E-binding protein (4EBP1) is considered a tumor suppressor. The exact molecular effects of 4EBP1 activation in cancer are still unknown. Surprisingly, 4EBP1 is a target of genomic copy number gains (Chr. 8p11) in breast and lung cancer. We notice that 4EBP1 gains are genetically...

Summary from GEO: "To investigate ribosome localization and gene expression dynamics during starvation in cancer cells, we performed RNA sequencing and ribosome profiling in RKO cells under fed and starved (12.5 uM arginine) conditions." Overall design from GEO: "Cells were kept under fed (400 uM arginine) or starved (12.5 uM arginine) conditions for 24 hours. RNA sequencing and ribosome profiling...

Summary from GEO: " Immune cell activation is a very rapid and concerted cellular response that requires coordination between cellular processes that occur in different compartments and on very different time scales. Here, we use ribosome profiling and deep RNA sequencing to define the acute mRNA translation changes that follow initial signaling events and enable subsequent events of T cell activation...

Description from Zenodo: "A Docker image for a slightly-modified version of the xpresspipe software, version 0.6.1. xpresspipe documentation: https://xpresspipe.readthedocs.io/en/latest/content/riboseq.html xpresspipe github: https://github.com/XPRESSyourself/XPRESSpipe" Meant for recreation of XPRESSpipe analysis in Salloum et al.

A code repository to rerun RiboDiff analysis and recreate all plots from Salloum et al. Description from GitHub: "This is the public version of the code for publication. Users can build the docker image from source and run all analyses from the paper."