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Python Codebase for SeqC (SEquence Quality Control)
- Authors
- Carr, Ambrose JamesChoi, KristyPe'er, Dana
- Description
SEQC is a python package that processes single-cell sequencing data in the cloud and analyzes it interactively on your local machine.
- Subject
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Sequence Analysis
- Access Rights
- Free to All
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Histone H1 loss drives lymphoma by disrupting 3D chromatin architecture
- Authors
- Yusufova, NevinTeater, MattCesarman, EthelMelnick, Ari M.1 more author(s)...
- Description
Summary from the GEO: "Linker histone H1 proteins bind to nucleosomes and cause chromatin compaction, although little is known about their biological functions. Histone H1 (HIST1H1B-E) mutations are highly recurrent in B-cell lymphomas and are present in solid tumors, but their cancer relevance and mechanism are unknown. Here we report that lymphoma-associated H1 alleles are genetic driver mutations...
- Subject
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B-LymphocytesGene SilencingGenes, Tumor SuppressorHistonesLymphomaSequence Analysis
- Access Rights
- Free to All
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Listeria seeligeri LS46 and LS59 Genome sequencing and assembly
- Description
BioProject description: "Genome sequencing of Listeria seeligeri LS46 and LS59". The whole genome sequencing of these listeriaphage enabled researchers to discover that AcrVIA1, an anti-CRISPR protein, interacts with the guide-exposed face of Cas13a, a (crRNA)-guided nuclease, preventing access to the target RNA and the conformational changes required for nuclease activation. A single dose of AcrVIA1...
- Subject
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ListeriaSequence AnalysisWhole Genome Sequencing
- Access Rights
- Free to All
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R Script for the analysis of "Gastrointestinal microbiota composition predicts peripheral inflammatory state during treatment of human tuberculosis"
- Authors
- Bhattarai, Shakti
- Description
R scripts used to for data analysis and figure support for the manuscript: Wipperman, M.F., Bhattarai, S.K., Vorkas, C.K. et al. Gastrointestinal microbiota composition predicts peripheral inflammatory state during treatment of human tuberculosis. Nat Commun 12, 1141 (2021). Data is available for download from Dropbox and the scripts listed are accessible from GitHub.
- Subject
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Sequence Analysis
- Access Rights
- Free to All