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scRNA-seq to study features of CD4conv and Treg cells in spleen and bone marrow of mice
- Authors
- Elias, SchlomoSchizas, MichailRudensky, Alexander Y.
- Description
Summary from GEO: "The aim of the study was to compare gene expression between Treg cells in the bone marrow and the spleen." Overall design from GEO: "2 male Foxp3-DTR-GFP were used for the study. Single cells suspension from BM and spleen were prepared, then enriched for CD4 by magneic beads and sorted by gating on CD4+TCRb+. GFP was used to differentiate between Tregs and CD4conv. CD4conv...
- Subject
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Bone MarrowCD4-Positive T-LymphocytesSequence Analysis, RNASpleenT-Lymphocytes, Regulatory
- Access Rights
- Free to All
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Next Generation Sequencing Analysis of OX40hi Treg and OX40lo Treg cells from mouse tumors and spleens
- Authors
- Tan, AdrianYang, NingDeng, Liang
- Description
Summary from GEO: "Based on RNA-seq technology, we studies gene expression profiles in Treg cells isolated from mouse tumors and spleens. We identified differential gene expressions comparing OX40hi Treg with OX40lo Treg cells from tumors and spleens. The difference of Trges in tumors and spleens were also identified." Overall design from GEO: "Foxp3-GFP mice were intradermally implanted with...
- Subject
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OX40 LigandRNA-Binding ProteinsSpleenT-Lymphocytes, Regulatory
- Access Rights
- Free to All