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Results Found: 18
  • Lung Adenocarcinoma (TCGA, PanCancer Atlas)

    Description

    This dataset contains summary data visualizations and clinical data from a broad sampling of 566 lung adenocarcinomas from 566 patients. The data was gathered as part of the PanCancer Atlas initiative, which aims to answer big, overarching questions about cancer by examining the full set of tumors characterized in the robust TCGA dataset. The clinical data includes mutation count, information about...

    Subject
    Adenocarcinoma of Lung
    DNA Mutational Analysis
    Access Rights
    Free to All
  • MSK-IMPACT Clinical Sequencing Cohort (MSKCC, Nat Med 2017): Targeted sequencing of 10,000 clinical cases using the MSK-IMPACT assay

    Description

    This dataset contains summary data visualizations and clinical data from the targeted sequencing of 10,000 clinical cases using the MSK-IMPACT assay. The clinical data includes mutation count, information about mutated genes, tumor mutational burden calculations, tissue site from which the sample was derived, tumor purity among other relevant data points. The data set also includes copy-number segment...

    Subject
    Adenocarcinoma
    Adenocarcinoma of Lung
    Adenocarcinoma, Mucinous
    Breast Neoplasms
    Carcinoma, Ductal, Breast
    Carcinoma, Hepatocellular
    Carcinoma, Lobular
    Carcinoma, Non-Small-Cell Lung
    Carcinoma, Renal Cell
    Carcinoma, Squamous Cell
    Carcinosarcoma
    Cholangiocarcinoma
    Colonic Neoplasms
    Colorectal Neoplasms
    Cystadenocarcinoma, Serous
    DNA Mutational Analysis
    Gallbladder Neoplasms
    Glioblastoma
    Liposarcoma
    Lung Neoplasms
    Lymphoma, Follicular
    Melanoma
    Mesothelioma
    Neoplasms, Squamous Cell
    Neurofibroma
    Oligodendroglioma
    Osteosarcoma
    Ovarian Neoplasms
    Pancreatic Neoplasms
    Prostatic Neoplasms
    Rectal Neoplasms
    Sarcoma
    Sarcoma, Synovial
    Squamous Cell Carcinoma of Head and Neck
    Stomach Neoplasms
    Thyroid Cancer, Papillary
    Urinary Bladder Neoplasms
    Uterine Neoplasms
    Uveal Neoplasms
    Access Rights
    Free to All
  • Thoracic PDX (MSK, Provisional): Targeted sequencing of thoracic PDX lines to characterize genetic alterations in 139 tumor/normal pairs via MSK-IMPACT.

    Description

    This dataset contains summary data visualizations and clinical data from a broad 183 samples of thoracic tumors from 77 patients. The data was generated by the Charles Rudin Lab, utilizing the MSK-IMPACT targeted sequencing test. The clinical data includes tumor type (based on the opensource OncoTree ontology developed at MSK), mutation count, information about mutated genes, patient demographics,...

    Subject
    Adenocarcinoma of Lung
    Carcinoma, Non-Small-Cell Lung
    DNA Mutational Analysis
    Lung Neoplasms
    Mesothelioma
    Access Rights
    Free to All
  • Lung Adenocarcinoma (TCGA, Firehose Legacy)

    Description

    TCGA Lung Adenocarcinoma. Source data from GDAC Firehose. Previously known as TCGA Provisional. This dataset contains summary data visualizations and clinical data from a broad sampling of 586 carcinomas from 584 patients. The data was gathered as part of the Broad Institute of MIT and Harvard Firehose initiative, a cancer analysis pipeline. The clinical data includes mutation count, information about...

    Subject
    Adenocarcinoma of Lung
    DNA Mutational Analysis
    Access Rights
    Free to All
  • Mixed cfDNA (MSKCC, 2020): IMPACT sequencing of 229 cell-free DNA (cfDNA) and associated tumor samples with matched normal

    Description

    This dataset contains the summary data visualizations and clinical data of IMPACT sequencing of 229 cell-free DNA (cfDNA) and associated tumor samples with matched normal from 118 patients. Clinical data includes: Cancer Type, Number of Samples Per Patient, Mutation Count, Fraction Genome Altered, Sex, Primary/Metastasis Sample Type, Collaboration Id, Gene Panel, Oncotree Code, Tumor/cfDNA Sample...

    Subject
    Adenocarcinoma
    Adenocarcinoma of Lung
    Breast Neoplasms
    Carcinoma, Ductal, Breast
    Carcinoma, Neuroendocrine
    Carcinoma, Renal Cell
    Carcinoma, Squamous Cell
    Cell-Free Nucleic Acids
    Choriocarcinoma
    Endodermal Sinus Tumor
    Melanoma
    Neoplasms, Germ Cell and Embryonal
    Neoplasms, Squamous Cell
    Neuroendocrine Tumors
    Prostatic Neoplasms
    Seminoma
    Small Cell Lung Carcinoma
    Urinary Bladder Neoplasms
    Access Rights
    Free to All
  • Non-Small Cell Cancer (MSKCC, Cancer Discov 2017): Targeted sequencing of 860 patients with metastatic lung adenocarcinoma

    Description

    This dataset contains the summary data visualizations and clinical data from targeted sequencing of 915 samples from 860 patients with metastatic lung adenocarcinoma. Clinical data includes: Number of Samples Per Patient, Mutation Count, Fraction Genome Altered, Diagnosis Age, Sex, Primary/Metastasis Sample Type, Chemotherapy, Clinical Trial, Driver Mutations, Durable Clinical Benefit, Gene Panel,...

    Subject
    Adenocarcinoma
    Adenocarcinoma of Lung
    Carcinoma, Non-Small-Cell Lung
    Lung Neoplasms
    Access Rights
    Free to All
  • Lung Adenocarcinoma (MSKCC, 2020): Targeted sequencing of 604 lung adenocarcinoma tumor/normal pairs via MSK-IMPACT

    Description

    This dataset contains the summary data visualizations and clinical data from targeted sequencing of 604 lung adenocarcinoma tumors from 604 patients via MSK-IMPACT. Clinical data includes: Mutation Count, Fraction Genome Altered, Sex, Age At Surgery, Clinical Nodal Status, CT Size, Diffusion lung capacity for carbon monoxide, FEV1, FGA Facets, Overall Survival Status, Pathologic Nodal Status Pathologic...

    Subject
    Adenocarcinoma
    Adenocarcinoma of Lung
    Lung Neoplasms
    Access Rights
    Free to All
  • Non-Small Cell Lung Cancer (MSKCC, J Clin Oncol 2018): IMPACT sequencing of 240 NSCLC tumor/normal pairs treated at MSKCC with anti-PD-(L)1 based therapy.

    Description

    This dataset contains the summary data visualizations and clinical data from IMPACT sequencing of 240 NSCLC tumor/normal pairs treated at MSKCC with anti-PD-(L)1 based therapy from 240 patients. Clinical data includes: Cancer Type, Mutation Count, Fraction Genome Altered, Sex, Durable Clinical Benefit, FGA, Gene Panel, IRB, Lines of treatment, Mutation Rate, Oncotree Code, PD-L1 Score (%), Smoker,...

    Subject
    Adenocarcinoma of Lung
    Carcinoma, Large Cell
    Carcinoma, Non-Small-Cell Lung
    Carcinoma, Squamous Cell
    Lung Neoplasms
    Access Rights
    Free to All
  • A collection of Whole-genome sequencing files from the Cancer Genome Atlas program on Adenocarcinoma, filtered from the GDC Data Portal

    Description

    The GDC Data Portal is a robust data-driven platform that allows cancer researchers and bioinformaticians to search and download cancer data for analysis. This dataset is a filtered search result in the GDC Data Portal for TCGA Project, Adenocarcinoma, Whole Genome Sequencing Reads. It consists of 196 BAM files and 99 cases.

    Subject
    Adenocarcinoma of Lung
    Access Rights
    Application Required
  • Characterizing an HSF1-dependent transcriptional program in metastatic lung adenocarcinoma

    Authors
    Hoj, Jacob P.
    Pendergast, Ann M.
    Description

    Summary from the GEO: "The purpose of this study was to identify gene targets differentially regulated by shRNA-mediated knockdown of the HSF1 transcription factor in the brain-metastatic lung adenocarcinoma cell line PC9-BrM3." Overall design from the GEO: "Samples were analyzed for differential gene expression in PC9-BrM3 cells transduced with shRNAs against NTC (non-target control) versus HSF1....

    Subject
    Adenocarcinoma of Lung
    Brain Neoplasms
    Heat Shock Transcription Factors
    Lung Neoplasms
    RNA, Small Interfering
    Access Rights
    Free to All