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Rectal Cancer (MSK,Nature Medicine 2019): MSK-IMPACT targeted sequencing of matched rectal cancer tumor and tumoroid samples
- Authors
- Ganesh, KarunaWu, ChaoO'Rourke, Kevin PatrickSzeglin, Bryan Charles46 more author(s)...
- Description
This dataset contains summary data visualizations and clinical data of rectal cancer tumoroids based on massively parallel sequencing using the custom, Food and Drug Administration (FDA)-cleared tumor-profiling panel MSK Integrated Mutation Profiling of Actionable Cancer Targets (MSK-IMPACT). The clinical data includes mutation count, information about mutated genes, Gene Panel, Impact TMB Score,...
- Subject
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DNA Mutational AnalysisRectal NeoplasmsRectal Neoplasms/genetics
- Access Rights
- Free to All
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Anaplastic Oligodendroglioma and Anaplastic Oligoastrocytoma (MSKCC, Neuro Oncol 2017): Genomic characterization using next generation sequencing (NGS) in 22 Anaplastic Oligodendroglioma and Anaplastic Oligoastrocytomas.
- Authors
- Thomas, Alissa A.Abrey, Lauren E.Terziev, RobertRaizer, Jeffrey J.24 more author(s)...
- Description
This dataset contains summary data visualizations and sequencing data of 22 anaplastic oligodendroglioma (AO) and anaplastic oligoastrocytoma (AOA) tumors from 19 patients following a trial using induction temozolomide (TMZ) followed by myeloablative high-dose chemotherapy (HDC) with autologous stem-cell transplant (ASCT) as a potential strategy to defer radiotherapy. The clinical data includes mutation...
- Subject
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Brain NeoplasmsChemoradiotherapyDNA Mutational AnalysisOligodendrogliomaTemozolomide
- Access Rights
- Free to All
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Bladder Cancer (MSKCC, Nat Genet 2016): Whole exome and targeted sequencing of 34 plasmacytoid-variant (signet ring cell) tumors of the bladder
- Authors
- Al-Ahmadie, HikmatIyer, Gopakumar VasudevaLee, Byron Hing LungScott, Sasinya Neka25 more author(s)...
- Description
Whole-exome and targeted sequencing of plasmacytoid bladder cancer, an aggressive histologic variant with a high risk of disease-specific mortality. This dataset contains summary data visualizations and sequencing data of 34 plasmacytoid-variant (signet ring cell) tumors of the bladder from 31 patients. Clinical data includes detailed cancer type, mutation count, information about mutated genes, patient...
- Subject
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DNA Mutational AnalysisPlasmacytoma/geneticsUrinary Bladder Neoplasms
- Access Rights
- Free to All
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Acral Melanoma (TGEN, Genome Res 2017): Whole exome sequencing and transcriptome analysis of 34 Acral Melanoma patients (33 with matched normals)
- Authors
- Liang, Winnie S.Hendricks, WilliamKiefer, JeffreySchmidt, Jessica22 more author(s)...
- Description
This dataset contains summary data visualizations and clinical data from a comprehensive genomic and transcriptomic analysis of 38 acral lentiginous melanomas (ALM) from 34 patients. The study was conducted to analyze ALM, a rare sun-shielded melanoma subtype of cutaneous melanoma (CM) which is associated with worse survival than other CM in an effort to delineate non-UV oncogenic mechanisms. The...
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Chromosome AberrationsDNA Mutational AnalysisMelanoma/geneticsMelanoma/pathologyTranscriptome
- Access Rights
- Free to All
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Whole Exome Sequencing of Six Signet Ring/Plasmacytoid Variant Bladder Tumors
- Authors
- Solit, David
- Description
In this study, six plasmacytoid bladder cancers were analyzed by whole exome sequencing. The results show loss of the CDH1 gene in every sample and correlate with E-cadherin loss of expression by immunohistochemistry. A separate validation cohort of plasmacytoid samples showed loss of E-cadherin expression by CDH1 mutation or promoter hypermethylation. The data includes information about the study,...
- Subject
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DNA Mutational AnalysisMutationPlasmacytoma/geneticsUrinary Bladder Neoplasms
- Access Rights
- Application Required
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Breast Invasive Carcinoma (TCGA, PanCancer Atlas) data
- Description
This dataset contains summary data visualizations and clinical data from a broad sampling of 1,084 breast invasive carcinomas from 1,084 patients. The data was gathered as part of the PanCancer Atlas initiative, which aims to answer big, overarching questions about cancer by examining the full set of tumors characterized in the robust TCGA dataset. The clinical data includes mutation count, information...
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Breast NeoplasmsCarcinoma, Ductal, BreastCarcinoma, LobularDNA Mutational Analysis
- Access Rights
- Free to All
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Brain Lower Grade Glioma (TCGA, PanCancer Atlas): Brain Lower Grade Glioma TCGA PanCancer data.
- Description
This dataset contains summary data visualizations and clinical data from a broad sampling of 514 brain lower grade gliomas from 514 patients. The data was gathered as part of the PanCancer Atlas initiative, which aims to answer big, overarching questions about cancer by examining the full set of tumors characterized in the robust TCGA dataset. The clinical data includes mutation count, information...
- Subject
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Brain NeoplasmsDNA Mutational Analysis
- Access Rights
- Free to All
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Acute Myeloid Leukemia (TCGA, PanCancer Atlas) data
- Description
This dataset contains summary data visualizations and clinical data from a broad sampling of over 200 acute myeloid leukemias from 200 patients. The data was gathered as part of the PanCancer Atlas initiative, which aims to answer big, overarching questions about cancer by examining the full set of tumors characterized in the robust TCGA dataset. The clinical data includes mutation count, information...
- Subject
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DNA Mutational AnalysisLeukemia, Myeloid, Acute
- Access Rights
- Free to All
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Bladder Urothelial Carcinoma (TCGA, PanCancer Atlas): Bladder Urothelial Carcinoma TCGA PanCancer data.
- Description
This dataset contains summary data visualizations and clinical data from a broad sampling of 411 bladder urothelial carcinomas from 411 patients. The data was gathered as part of the PanCancer Atlas initiative, which aims to answer big, overarching questions about cancer by examining the full set of tumors characterized in the robust TCGA dataset. The clinical data includes mutation count, information...
- Subject
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DNA Mutational AnalysisUrinary Bladder Neoplasms
- Access Rights
- Free to All
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Adrenocortical Carcinoma (TCGA, PanCancer Atlas) data
- Description
This dataset contains summary data visualizations and clinical data from a broad sampling of 92 adrenocortical carcinomas from 92 patients. The data was gathered as part of the PanCancer Atlas initiative, which aims to answer big, overarching questions about cancer by examining the full set of tumors characterized in the robust TCGA dataset. The clinical data includes mutation count, information about...
- Subject
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Adrenocortical CarcinomaDNA Mutational Analysis
- Access Rights
- Free to All