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Results Found: 95
  • Rectal Cancer (MSK,Nature Medicine 2019): MSK-IMPACT targeted sequencing of matched rectal cancer tumor and tumoroid samples

    Authors
    Ganesh, Karuna
    Wu, Chao
    O'Rourke, Kevin Patrick
    Szeglin, Bryan Charles
    46 more author(s)...
    Description

    This dataset contains summary data visualizations and clinical data of rectal cancer tumoroids based on massively parallel sequencing using the custom, Food and Drug Administration (FDA)-cleared tumor-profiling panel MSK Integrated Mutation Profiling of Actionable Cancer Targets (MSK-IMPACT). The clinical data includes mutation count, information about mutated genes, Gene Panel, Impact TMB Score,...

    Subject
    DNA Mutational Analysis
    Rectal Neoplasms
    Rectal Neoplasms/genetics
    Access Rights
    Free to All
  • Anaplastic Oligodendroglioma and Anaplastic Oligoastrocytoma (MSKCC, Neuro Oncol 2017): Genomic characterization using next generation sequencing (NGS) in 22 Anaplastic Oligodendroglioma and Anaplastic Oligoastrocytomas.

    Authors
    Thomas, Alissa A.
    Abrey, Lauren E.
    Terziev, Robert
    Raizer, Jeffrey J.
    24 more author(s)...
    Description

    This dataset contains summary data visualizations and sequencing data of 22 anaplastic oligodendroglioma (AO) and anaplastic oligoastrocytoma (AOA) tumors from 19 patients following a trial using induction temozolomide (TMZ) followed by myeloablative high-dose chemotherapy (HDC) with autologous stem-cell transplant (ASCT) as a potential strategy to defer radiotherapy. The clinical data includes mutation...

    Subject
    Brain Neoplasms
    Chemoradiotherapy
    DNA Mutational Analysis
    Oligodendroglioma
    Temozolomide
    Access Rights
    Free to All
  • Bladder Cancer (MSKCC, Nat Genet 2016): Whole exome and targeted sequencing of 34 plasmacytoid-variant (signet ring cell) tumors of the bladder

    Authors
    Al-Ahmadie, Hikmat
    Iyer, Gopakumar Vasudeva
    Lee, Byron Hing Lung
    Scott, Sasinya Neka
    25 more author(s)...
    Description

    Whole-exome and targeted sequencing of plasmacytoid bladder cancer, an aggressive histologic variant with a high risk of disease-specific mortality. This dataset contains summary data visualizations and sequencing data of 34 plasmacytoid-variant (signet ring cell) tumors of the bladder from 31 patients. Clinical data includes detailed cancer type, mutation count, information about mutated genes, patient...

    Subject
    DNA Mutational Analysis
    Plasmacytoma/genetics
    Urinary Bladder Neoplasms
    Access Rights
    Free to All
  • Acral Melanoma (TGEN, Genome Res 2017): Whole exome sequencing and transcriptome analysis of 34 Acral Melanoma patients (33 with matched normals)

    Authors
    Liang, Winnie S.
    Hendricks, William
    Kiefer, Jeffrey
    Schmidt, Jessica
    22 more author(s)...
    Description

    This dataset contains summary data visualizations and clinical data from a comprehensive genomic and transcriptomic analysis of 38 acral lentiginous melanomas (ALM) from 34 patients. The study was conducted to analyze ALM, a rare sun-shielded melanoma subtype of cutaneous melanoma (CM) which is associated with worse survival than other CM in an effort to delineate non-UV oncogenic mechanisms. The...

    Subject
    Chromosome Aberrations
    DNA Mutational Analysis
    Melanoma/genetics
    Melanoma/pathology
    Transcriptome
    Access Rights
    Free to All
  • Whole Exome Sequencing of Six Signet Ring/Plasmacytoid Variant Bladder Tumors

    Authors
    Solit, David
    Description

    In this study, six plasmacytoid bladder cancers were analyzed by whole exome sequencing. The results show loss of the CDH1 gene in every sample and correlate with E-cadherin loss of expression by immunohistochemistry. A separate validation cohort of plasmacytoid samples showed loss of E-cadherin expression by CDH1 mutation or promoter hypermethylation. The data includes information about the study,...

    Subject
    DNA Mutational Analysis
    Mutation
    Plasmacytoma/genetics
    Urinary Bladder Neoplasms
    Access Rights
    Application Required
  • Breast Invasive Carcinoma (TCGA, PanCancer Atlas) data

    Description

    This dataset contains summary data visualizations and clinical data from a broad sampling of 1,084 breast invasive carcinomas from 1,084 patients. The data was gathered as part of the PanCancer Atlas initiative, which aims to answer big, overarching questions about cancer by examining the full set of tumors characterized in the robust TCGA dataset. The clinical data includes mutation count, information...

    Subject
    Breast Neoplasms
    Carcinoma, Ductal, Breast
    Carcinoma, Lobular
    DNA Mutational Analysis
    Access Rights
    Free to All
  • Brain Lower Grade Glioma (TCGA, PanCancer Atlas): Brain Lower Grade Glioma TCGA PanCancer data.

    Description

    This dataset contains summary data visualizations and clinical data from a broad sampling of 514 brain lower grade gliomas from 514 patients. The data was gathered as part of the PanCancer Atlas initiative, which aims to answer big, overarching questions about cancer by examining the full set of tumors characterized in the robust TCGA dataset. The clinical data includes mutation count, information...

    Subject
    Brain Neoplasms
    DNA Mutational Analysis
    Access Rights
    Free to All
  • Acute Myeloid Leukemia (TCGA, PanCancer Atlas) data

    Description

    This dataset contains summary data visualizations and clinical data from a broad sampling of over 200 acute myeloid leukemias from 200 patients. The data was gathered as part of the PanCancer Atlas initiative, which aims to answer big, overarching questions about cancer by examining the full set of tumors characterized in the robust TCGA dataset. The clinical data includes mutation count, information...

    Subject
    DNA Mutational Analysis
    Leukemia, Myeloid, Acute
    Access Rights
    Free to All
  • Bladder Urothelial Carcinoma (TCGA, PanCancer Atlas): Bladder Urothelial Carcinoma TCGA PanCancer data.

    Description

    This dataset contains summary data visualizations and clinical data from a broad sampling of 411 bladder urothelial carcinomas from 411 patients. The data was gathered as part of the PanCancer Atlas initiative, which aims to answer big, overarching questions about cancer by examining the full set of tumors characterized in the robust TCGA dataset. The clinical data includes mutation count, information...

    Subject
    DNA Mutational Analysis
    Urinary Bladder Neoplasms
    Access Rights
    Free to All
  • Adrenocortical Carcinoma (TCGA, PanCancer Atlas) data

    Description

    This dataset contains summary data visualizations and clinical data from a broad sampling of 92 adrenocortical carcinomas from 92 patients. The data was gathered as part of the PanCancer Atlas initiative, which aims to answer big, overarching questions about cancer by examining the full set of tumors characterized in the robust TCGA dataset. The clinical data includes mutation count, information about...

    Subject
    Adrenocortical Carcinoma
    DNA Mutational Analysis
    Access Rights
    Free to All