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  • Cryo-EM structure of Cas13(crRNA)

    Authors
    Jia, Ning
    Meeske, Alexander J.
    Marraffini, Luciano A.
    Patel, Dinshaw J.
    Description

    This deposit in the Research Collaboratory for Structural Bioinformatics Protein Data Base (PDB) includes electron microscopy data used for modeling the Cryo-EM structure of Cas13(crRNA). The main summary display for this entry includes information on the experimental data, validation, macromolecules and version history. Data is provided for download as FASTA sequence format, the Protein Data Bases...

    Subject
    Clustered Regularly Interspaced Short Palindromic Repeats
    CRISPR-Associated Proteins
    CRISPR-Cas Systems
    DNA-Directed RNA Polymerases
    Listeria
    Access Rights
    Free to All
  • Listeria seeligeri LS46 and LS59 Genome sequencing and assembly

    Description

    BioProject description: "Genome sequencing of Listeria seeligeri LS46 and LS59". The whole genome sequencing of these listeriaphage enabled researchers to discover that AcrVIA1, an anti-CRISPR protein, interacts with the guide-exposed face of Cas13a, a (crRNA)-guided nuclease, preventing access to the target RNA and the conformational changes required for nuclease activation. A single dose of AcrVIA1...

    Subject
    Listeria
    Sequence Analysis
    Whole Genome Sequencing
    Access Rights
    Free to All
  • Cryo-EM structure of AcrVIA1-Cas13(crRNA) complex

    Authors
    Jia, Ning
    Meeske, Alexander J.
    Marraffini, Luciano A.
    Patel, Dinshaw J.
    Description

    This deposit in the Research Collaboratory for Structural Bioinformatics Protein Data Base (PDB) includes cryogenic electron microscopy data identifying the Cryo-EM structure of AcrVIA1-Cas13(crRNA) complex. The main summary display for this entry includes information on the experimental method and validation, macromolecules and version history. Data is provided for download as FASTA sequence format,...

    Subject
    Clustered Regularly Interspaced Short Palindromic Repeats
    CRISPR-Associated Proteins
    CRISPR-Cas Systems
    DNA-Directed RNA Polymerases
    Listeria
    Access Rights
    Free to All