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Pancreatic Adenocarcinoma (TCGA, Firehose Legacy)
- Description
TCGA Pancreatic Adenocarcinoma. Source data from GDAC Firehose. Previously known as TCGA Provisional. This dataset contains summary data visualizations and clinical data from a broad sampling of 186 carcinomas from 185 patients. The data was gathered as part of the Broad Institute of MIT and Harvard Firehose initiative, a cancer analysis pipeline. The clinical data includes mutation count, information...
- Subject
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AdenocarcinomaDNA Mutational AnalysisPancreatic Neoplasms
- Access Rights
- Free to All
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Limited heterogeneity of known driver gene mutations among the metastases of individual patients with pancreatic cancer
- Description
Dataset Description from EGA: "Sequencing of untreated pancreatic cancer metastases and primary tumor sections. " Abstract from the MSK Synapse article to further understand the dataset in EGA: "The extent of heterogeneity among driver gene mutations present in naturally occurring metastases-that is, treatment-naive metastatic disease-is largely unknown. To address this issue, we carried out 60x...
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Pancreatic Neoplasms
- Access Rights
- Application Required
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Whole Genome Scan for Pancreatic Cancer Risk in the Pancreatic Cancer Cohort Consortium and Pancreatic Cancer Case-Control Consortium (PanScan)
- Authors
- Amundadottir, LaufeyWolpin, BrianStolzenberg-Solomon, Rachael
- Description
Study Description from the dbGaP: "Within the framework of the NCI-sponsored Cohort Consortium, investigators from 12 prospective epidemiologic cohorts formed the Pancreatic Cancer Cohort Consortium in 2006. This study, also known as "PanScan", is funded by the National Cancer Institute (NCI) and involves conducting a genome-wide association study (GWAS) of common genetic variants to identify markers...
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Pancreatic Neoplasms
- Access Rights
- Application Required
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Pancreatic Cancer Case Control Association Study
- Description
Study Description from the dbGaP: "Pancreatic cancer is the 4th leading cause of cancer death in the United States. This is in large part due to the rapidly fatal course of this disease, as the vast majority of patients die within months of diagnosis and the five-year survival rate is less than 5. We have brought together over 8000 participants from 9 studies of pancreatic cancer, to conduct a GWAS...
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Pancreatic Neoplasms
- Access Rights
- Application Required
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Multi-region sequencing of tumor samples from PDAC patients
- Description
Description from EGA: "This study includes 542 of multi-region sampled whole exome sequencing data from 83 pancreatic cancer patients in 6 individual experiments : Kras wildtype, local recurrence, treatment-naive (MetomeV2), radiotherapy plus chemotherapy (Radome), chemotherapy-only group (Treatome) and Proj_B-100-478." Dataset is also accessioned as a study, associated with publication "The Evolutionary...
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ChemoradiotherapyDrug TherapyExome SequencingGenes, rasNeoplasm Recurrence, LocalPancreatic NeoplasmsRadiotherapy
- Access Rights
- Author approval required