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Results Found: 8
  • Breast Invasive Carcinoma (TCGA, PanCancer Atlas) data

    Description

    This dataset contains summary data visualizations and clinical data from a broad sampling of 1,084 breast invasive carcinomas from 1,084 patients. The data was gathered as part of the PanCancer Atlas initiative, which aims to answer big, overarching questions about cancer by examining the full set of tumors characterized in the robust TCGA dataset. The clinical data includes mutation count, information...

    Subject
    Breast Neoplasms
    Carcinoma, Ductal, Breast
    Carcinoma, Lobular
    DNA Mutational Analysis
    Access Rights
    Free to All
  • MSK-IMPACT Clinical Sequencing Cohort (MSKCC, Nat Med 2017): Targeted sequencing of 10,000 clinical cases using the MSK-IMPACT assay

    Description

    This dataset contains summary data visualizations and clinical data from the targeted sequencing of 10,000 clinical cases using the MSK-IMPACT assay. The clinical data includes mutation count, information about mutated genes, tumor mutational burden calculations, tissue site from which the sample was derived, tumor purity among other relevant data points. The data set also includes copy-number segment...

    Subject
    Adenocarcinoma
    Adenocarcinoma of Lung
    Adenocarcinoma, Mucinous
    Breast Neoplasms
    Carcinoma, Ductal, Breast
    Carcinoma, Hepatocellular
    Carcinoma, Lobular
    Carcinoma, Non-Small-Cell Lung
    Carcinoma, Renal Cell
    Carcinoma, Squamous Cell
    Carcinosarcoma
    Cholangiocarcinoma
    Colonic Neoplasms
    Colorectal Neoplasms
    Cystadenocarcinoma, Serous
    DNA Mutational Analysis
    Gallbladder Neoplasms
    Glioblastoma
    Liposarcoma
    Lung Neoplasms
    Lymphoma, Follicular
    Melanoma
    Mesothelioma
    Neoplasms, Squamous Cell
    Neurofibroma
    Oligodendroglioma
    Osteosarcoma
    Ovarian Neoplasms
    Pancreatic Neoplasms
    Prostatic Neoplasms
    Rectal Neoplasms
    Sarcoma
    Sarcoma, Synovial
    Squamous Cell Carcinoma of Head and Neck
    Stomach Neoplasms
    Thyroid Cancer, Papillary
    Urinary Bladder Neoplasms
    Uterine Neoplasms
    Uveal Neoplasms
    Access Rights
    Free to All
  • Breast Invasive Carcinoma (TCGA, Firehose Legacy)

    Description

    TCGA Breast Invasive Carcinoma. Source data from GDAC Firehose. Previously known as TCGA Provisional. This dataset contains summary data visualizations and clinical data from a broad sampling of 1,108 carcinomas from 1,101 patients. The data was gathered as part of the Broad Institute of MIT and Harvard Firehose initiative, a cancer analysis pipeline. The clinical data includes mutation count, information...

    Subject
    Breast Neoplasms
    Carcinoma, Ductal, Breast
    Carcinoma, Lobular
    DNA Mutational Analysis
    Skin Neoplasms
    Access Rights
    Free to All
  • Mixed cfDNA (MSKCC, 2020): IMPACT sequencing of 229 cell-free DNA (cfDNA) and associated tumor samples with matched normal

    Description

    This dataset contains the summary data visualizations and clinical data of IMPACT sequencing of 229 cell-free DNA (cfDNA) and associated tumor samples with matched normal from 118 patients. Clinical data includes: Cancer Type, Number of Samples Per Patient, Mutation Count, Fraction Genome Altered, Sex, Primary/Metastasis Sample Type, Collaboration Id, Gene Panel, Oncotree Code, Tumor/cfDNA Sample...

    Subject
    Adenocarcinoma
    Adenocarcinoma of Lung
    Breast Neoplasms
    Carcinoma, Ductal, Breast
    Carcinoma, Neuroendocrine
    Carcinoma, Renal Cell
    Carcinoma, Squamous Cell
    Cell-Free Nucleic Acids
    Choriocarcinoma
    Endodermal Sinus Tumor
    Melanoma
    Neoplasms, Germ Cell and Embryonal
    Neoplasms, Squamous Cell
    Neuroendocrine Tumors
    Prostatic Neoplasms
    Seminoma
    Small Cell Lung Carcinoma
    Urinary Bladder Neoplasms
    Access Rights
    Free to All
  • Breast Cancer (MSK, Cancer Cell 2018): Targeted Sequencing of tumor/normal sample pairs from 1918 Breast cancers.

    Description

    This dataset contains the summary data visualizations and clinical data from targeted sequencing of tumor/normal sample pairs from 1,918 Breast cancers from 1,756 patients. Clinical data includes: Cancer Type, Number of Samples Per Patient, Mutation Count, Fraction Genome Altered, Sample Type, Sex, Disease Free (Months), Disease Free Event, ER PCT Primary, ER Status of Sequenced Sample, ER Status...

    Subject
    Breast Carcinoma In Situ
    Breast Neoplasms
    Carcinoma, Adenoid Cystic
    Carcinoma, Ductal, Breast
    Carcinoma, Lobular
    Access Rights
    Free to All
  • Data from: Clonal relatedness between lobular carcinoma in situ and synchronous malignant lesions

    Authors
    Andrade, Victor P.
    Ostrovnaya, Irina
    Seshan, Venkatraman
    Morrogh, Mary
    6 more author(s)...
    Description

    Summary from Dryad: "Abstract: INTRODUCTION: Lobular carcinoma in situ (LCIS) has been accepted as a marker of risk for the development of invasive breast cancer, yet modern models of breast carcinogenesis include LCIS as a precursor of low-grade carcinomas. We provide evidence favoring a clonal origin for LCIS and synchronous estrogen receptor-positive malignant lesions of the ductal and lobular...

    Subject
    Biomarkers, Tumor
    Carcinoma, Ductal, Breast
    Carcinoma, Lobular
    Access Rights
    Free to All
  • MSK MetTropism (MSK, Cell 2021)

    Authors
    Nguyen, Bastien
    Fong, Christopher
    Luthra, Anisha
    Smith, Shaleigh A.
    71 more author(s)...
    Description

    Description from cBioPortal: "MSK-MET (Memorial Sloan Kettering - Metastatic Events and Tropisms) is an integrated pan-cancer cohort of tumor genomic and clinical outcome data from 25,000 patients. We analyzed this dataset to identify associations between tumor genomic alterations and patterns of metastatic dissemination across 50 tumor types. We found that chromosomal instability is strongly correlated...

    Subject
    Adenocarcinoma of Lung
    Carcinoma, Ductal, Breast
    Chromosomal Instability
    Genomics
    Neoplasm Metastasis
    Prostatic Neoplasms
    Access Rights
    Free to All
  • Lobular Carcinomas In Situ Display Intra-Lesion Genetic Heterogeneity and Clonal Evolution in the Progression to Invasive Disease

    Authors
    King, Tari A.
    Reis-Filho, Jorge S.
    Description

    Description from dbGaP: "This study comprises prospectively accrued, microdissected fresh frozen samples of multifocal lobular carcinoma in situ (LCIS), ductal carcinoma in situ (DCIS), invasive lobular carcinoma and invasive ductal carcinoma from patients undergoing prophylactic or therapeutic mastectomies after a diagnosis on LCIS diagnosed and managed at Memorial Sloan Kettering Cancer Center...

    Subject
    Carcinoma, Ductal, Breast
    Carcinoma, Lobular
    Exome Sequencing
    Mastectomy
    Access Rights
    Application Required