Summary from the GEO: "RNA-sequencing of Rreb1+/+ and Rreb1-/- embryonic day 7.5 mouse embryos" Overall design from the GEO: "RNA-sequencing of Rreb1+/+ and Rreb1-/- embryonic day 7.5 mouse embryos. Mouse embryos were collected at embryonic day 7.5 from intercrosses between Rreb1+/- mice. Samples of the parietal endoderm were taken during dissection for genotyping. Embryos were immediately frozen...

This deposit in the Research Collaboratory for Structural Bioinformatics Protein Data Base (PDB) includes cryogenic electron microscopy data identifying the structure of human SHLD2-SHLD3-REV7-TRIP13(E253Q) complex. The main summary display for this entry includes information on the experimental method, validation, macromolecules and small molecules in the deposit, as well as entry history. Data...

This deposit in the Research Collaboratory for Structural Bioinformatics Protein Data Base (PDB) includes x-ray diffraction data identifying the crystal structure of human SHLD2-SHLD3-REV7 complex. The main summary display for this entry includes information on the experimental method, validation, macromolecules in the deposit, as well as entry history. Data is provided for download as FASTA sequence...

This deposit in the Research Collaboratory for Structural Bioinformatics Protein Data Base (PDB) includes x-ray diffraction data identifying the crystal structure of human REV7(R124A)-SHLD3(35-58) complex. The main summary display for this entry includes information on the experimental method, validation, macromolecules in the deposit, as well as entry history. Data is provided for download as FASTA...

This deposit in the Research Collaboratory for Structural Bioinformatics Protein Data Base (PDB) includes x-ray diffraction data identifying the crystal structure of the K. lactis Rad5 (Hg-derivative). The main summary display for this entry includes information on the experimental method, validation, macromolecules and small molecules in the deposit, as well as entry history and funding information....

This deposit in the Research Collaboratory for Structural Bioinformatics Protein Data Base (PDB) includes x-ray diffraction data identifying the crystal structure of the K. lactis Rad5. The main summary display for this entry includes information on the experimental method, validation, macromolecules and small molecules in the deposit, as well as entry history and funding information. Data is provided...

Summary from the GEO: "Misregulation of long non-coding RNA genes has been linked to a wide variety of cancer types. Here we report on Mammary Tumor Associated RNA 25 (MaTAR25), a nuclear enriched and chromatin associated lncRNA that plays a role in mammary tumor cell proliferation, migration, and invasion, both in vitro and in vivo. MaTAR25 functions by interacting with purine rich element binding...

From Dryad summary: "Abstract: Deficiency in several of the classical human RAD51 paralogs [RAD51B, RAD51C, RAD51D, XRCC2 and XRCC3] is associated with cancer predisposition and Fanconi anemia. To investigate their functions, isogenic disruption mutants for each were generated in non-transformed MCF10A mammary epithelial cells and in transformed U2OS and HEK293 cells. In U2OS and HEK293 cells, viable...