Study Description from dbGaP:"Discovery, Biology, and Risk of Inherited Variants in Breast Cancer (DRIVE) was one of five projects funded in 2010 as part of the NCI's Genetic Associations and Mechanisms in Oncology (GAME-ON) initiative (http://epi.grants.cancer.gov/gameon/). GAME-ON's overall goal was to foster an intra-disciplinary and collaborative approach to the translation of promising research...

Study Description from dbGaP: "The data come from 40 studies participating in the Consortium of Investigators of Modifiers of BRCA1/2 (CIMBA). CIMBA recruits individuals with pathogenic mutations in BRCA1 or BRCA2. The majority of carriers were recruited through cancer genetics clinics offering genetic testing, and were enrolled into national or regional studies. The remainder were identified by population-based...

Method for Data Collection to GWAS Catalog submission: "The GWAS conducted by an international consortium group involved 1980 patients with severe acute respiratory failure induced by COVID-19 at seven hospitals in Italy and Spain [7]. After quality control, the final case-control cohort included 835 patients and 1255 control participants from Italy and 775 patients and 950 control participants from...

Method for Data Collection to GWAS Catalog submission: "The GWAS conducted by an international consortium group involved 1980 patients with severe acute respiratory failure induced by COVID-19 at seven hospitals in Italy and Spain [7]. After quality control, the final case-control cohort included 835 patients and 1255 control participants from Italy and 775 patients and 950 control participants from...

Description from dbGaP: "This study funded by the National Cancer Institute (NCI) involves conducting a genome-wide association study of common genetic variants to identify markers of susceptibility to bladder cancer. This bladder GWAS has led to the discovery of three novel regions in the genome associated with bladder cancer risk. Cases were defined as individuals having histologically confirmed...

Description from dbGaP: "This study compared Ashkenazi Jewish individuals with Stage IV metastatic colon cancer to those with non-metastatic Stage I or II colon cancers. A genome-wide association study, using a 2-stage design, identified a significant association with rs60745952."