Summary from GEO: "We performed single cell RNA sequencing with eight patient derived xenograft samples to identify quiescent cancer stem cells in glioblastoma. Additionally two samples treated with temozolomide was sequenced to examine the evolution of the cancer stem cells upon chemotherapeutics." Overall design from GEO: "Whole transcriptome single cell RNA sequencing with 10X method."

Summary from GEO: "In lung and prostate adenocarcinomas, neuroendocrine (NE) transformation to an aggressive derivative resembling small cell lung cancer (SCLC) is associated with poor prognosis. We previously described dependency of SCLC on the nuclear transporter exportin 1. Here we explored the role of exportin 1 in NE transformation. We observed upregulated exportin 1 in lung and prostate pre-transformation...

Summary from GEO: "Transcriptome profiling analysis was performed in 22 human prostate cancer organoids, 6 patient-derived xenografts (PDXs) and 7 cell lines." Overall design from GEO: "Transcriptome analysis of patient derived prostate cancer organoids and xenografts Please note that the "totalDf_rlog.csv" is a gene expression analysis of all our 33 uploaded RNA-seq data as well as publicly...

Summary from GEO: "Chromatin accessibility profiling analsis was performed in 22 human prostate cancer organoid, 6 Xenografts and 7 cell lines." Overall design from GEO: "ATAC-Seq of MSK-PCa series of Patient Derived Organoids and Xenografts, and prostate cell lines Please note that the processed data includes 5 samples (MSKEF1/PARCB1/PARCB3/PARCB6/PARCB8) from another study GSE118207: GSM3320999:...

Summary from GEO: "The enteric nervous system (ENS) is derived from both the vagal and sacral component of the neural crest (NC). Here, we present the derivation of sacral ENS precursors from human PSCs via timed exposure to FGF, WNT and to GDF11 to enable posterior patterning and transition from posterior trunk to sacral NC identity respectively. Using a SOX2::H2B-tdTomato/ T::H2B-GFP dual reporter...

Summary from GEO: "The enteric nervous system (ENS) is derived from both the vagal and sacral component of the neural crest (NC). Here, we present the derivation of sacral ENS precursors from human PSCs via timed exposure to FGF, WNT and to GDF11 to enable posterior patterning and transition from posterior trunk to sacral NC identity respectively. Using a SOX2::H2B-tdTomato/ T::H2B-GFP dual reporter...

Description from dbGaP: "Targeted capture sequencing of 341 cancer associated genes in thoracic patient-derived xenografts."