This dataset contains summary data visualizations and clinical data from a broad sampling of 500 thyroid carcinomas from 499 patients. The data was gathered as part of the PanCancer Atlas initiative, which aims to answer big, overarching questions about cancer by examining the full set of tumors characterized in the robust TCGA dataset. The clinical data includes mutation count, information about...

TCGA Thyroid Carcinoma. Source data from GDAC Firehose. Previously known as TCGA Provisional. This dataset contains summary data visualizations and clinical data from a broad sampling of 516 carcinomas from 508 patients. The data was gathered as part of the Broad Institute of MIT and Harvard Firehose initiative, a cancer analysis pipeline. The clinical data includes mutation count, information about...

This dataset contains the summary data visualizations and clinical data of Poorly-Differentiated and Anaplastic Thyroid Cancers with targeted sequencing of 341 cancer genes from 117 patient-derived PDTCs and ATCs. Clinical data includes: Mutation Count, Fraction Genome Altered, Diagnosis Age, Overall Survival Status, Metastasis/Primary Sample type, Patient Sex, AJCC Tumor Stage Code, Cytological Phenotype,...

Dataset Summary Description: "The Angiosarcoma Project is an ongoing patient-driven initiative. This archived Angiosarcoma Project dataset was analyzed in the linked Nature Medicine 2020 manuscript, and is derived from 48 samples from 36 angiosarcoma patients. Angiosarcoma tumor specimens (FFPE) were subjected to whole-exome sequencing (along with matched germline whole-exome sequencing). In addition...

Dataset Summary Description: "This provisional dataset is currently derived from 83 samples, including tumor specimens (FFPE and cfDNA) from 62 angiosarcoma patients subjected to WES (along with matched germline WES). This study includes genomic data, patient-reported data (pre-pended as PRD), medical record data (MedR), and pathology report data (PATH). As these data were generated in a research...

Summary from the GEO: "BACKGROUND. Poorly-differentiated (PDTC) and anaplastic (ATC) thyroid cancers are rare and frequently lethal tumors, which so far have not been subjected to comprehensive genetic characterization. METHODS. We performed next generation sequencing of 341 cancer genes in 117 PDTCs and ATCs, and a transcriptomic analysis of a representative subset of 37 tumors. Results were analyzed...

Summary from GEO: "We performed high-throughput RNA sequencing of stable lines with dox-inducible expression of sh-mirE-YAP or of the constitutively nuclear YAPS127A mutant to investigate YAP dependency and its role in tumorogenesis." Overall design from GEO: "mRNA profiles of human thyroid cancer cell lines treated with/without doxycyclin to express sh-mirE-YAP or of the constitutively nuclear...

Summary from GEO: "We performed high-throughput RNA sequencing of tumor cells sorted from YAPS127A and BrafV600E/YAPS127A to investigate YAP dependency and driver cooperativity in thyroid tumor progression." Overall design from GEO: "mRNA profiles of thyroid cancer cells from YAPS127A and BrafV600E/YAPS127A mice."