Search Tips
of 1 Next >
Results Found: 3
  • Germ Cell Tumors and Shared Leukemias: Targeted and WES sequencing of germ cell tumor and shared leukemia samples

    Description

    This dataset contains the summary data visualizations and clinical data of 21 samples from 11 patients of targeted and WES sequencing of germ cell tumor and shared leukemia samples. Clinical data includes: Cancer Type, Number of Samples per Patient, Mutation Count, Fraction Genome Altered, Specimen Preservation Type, Platform and Somatic Status. The plaintext components of the dataset can be downloaded...

    Subject
    Histiocytic Sarcoma
    Killer Cells, Natural
    Leukemia, Myeloid, Acute
    Leukemia, Myelomonocytic, Chronic
    Lymphohistiocytosis, Hemophagocytic
    Lymphoma, T-Cell
    Myelodysplastic Syndromes
    Neoplasms, Germ Cell and Embryonal
    Access Rights
    Free to All
  • Myelodysplastic (MSKCC, 2020): Single-cell genomics reveals the genetic and molecular bases for escape from mutational epistasis in myeloid neoplasms

    Description

    This dataset contains the summary data visualizations and clinical data from 4,231 myeloid neoplasm samples from 4,231 patients. Clinical data includes: Cancer Type, Cancer Type Detailed, Mutation Count, Oncotree Code, Sequencing Type, Somatic Status, Study. The plaintext components of the dataset can be downloaded as a tar file. The clinical data can be downloaded as a tsv file.

    Subject
    Acute monoblastic/monocytic leukemia
    Anemia, Refractory
    Anemia, Refractory, with Excess of Blasts
    Anemia, Sideroblastic
    Leukemia, Erythroblastic, Acute
    Leukemia, Megakaryoblastic, Acute
    Leukemia, Myelogenous, Chronic, BCR-ABL Positive
    Leukemia, Myeloid, Acute
    Leukemia, Myelomonocytic, Acute
    Leukemia, Myelomonocytic, Chronic
    Mastocytosis
    Myelodysplastic Syndromes
    Myelodysplastic-Myeloproliferative Diseases
    Oncogene Proteins, Fusion
    Polycythemia Vera
    Primary Myelofibrosis
    Sarcoma, Myeloid
    Thrombocythemia, Essential
    Access Rights
    Free to All
    Local Expert
    Papaemmanuil, Elli
  • (Metabolome analysis data): Mutant ASXL1 induces age-related expansion of phenotypic hematopoietic stem cells through activation of Akt/mTOR pathway

    Authors
    Kitamura, Toshio
    Description

    Description from MassIVE: Somatic mutations of ASXL1 are frequently detected in age-related clonal hematopoiesis (CH). However, how ASXL1 mutations drive CH remains elusive. Using knockin (KI) mice expressing a C-terminally truncated form of ASXL1-mutant (ASXL1-MT), we examined the influence of ASXL1-MT on physiological aging in hematopoietic stem cells (HSCs). HSCs expressing ASXL1-MT display competitive...

    Subject
    Clonal Hematopoiesis
    Hematopoietic Stem Cells
    Metabolome
    Myelodysplastic Syndromes
    Access Rights
    Free to All