TCGA Lymphoid Neoplasm Diffuse Large B-cell Lymphoma. Source data from GDAC Firehose. Previously known as TCGA Provisional. This dataset contains summary data visualizations and clinical data from a broad sampling of 48 carcinomas from 48 patients. The data was gathered as part of the Broad Institute of MIT and Harvard Firehose initiative, a cancer analysis pipeline. The clinical data includes mutation...

Summary from the GEO: "Complete Amplicon Sequencing of a 500bp V(D)J recombination products from proB cells sorted from control and Setd2KO mice to Vh558, Vh7183 and Vhq52 variable gene familes to JH4 joining gene fragment to determine CDR3. Genomic DNA from proB cells (B220+Cd43+IgM-CD25-) sorted from control and Setd2 knockout mice were isolated and subjected to V(D)J recombination PCR using a primer...

Summary from the GEO: "We study the role of loss of Setd2 and H3K36me3 in early B cell development through NGS methods including RNA, ChIP and ATAC Seq of sorted B cell populations of control and Setd2KO primary B cells from mice. From age-matched littermate controls and Setd2KO mouse, we sorted early proB cells (B220+CD43+CD19-Cd25-IgM-) and performed ATAC-seq, RNA-Seq, and ChIP-seq using an antibody...

Summary from the GEO: "Transcript analysis of RNA from murine proB cells to determine B cell repertoire and variable gene usage. RNA proB cells (B220+Cd43+IgM-CD25-) sorted from control and Setd2 knockout mice was analyzed for expression and use in the TRUST B/T cell repertoire algorithm."

This dataset contains the summary data visualizations and clinical data from targeted sequencing of 34 lymphoma cell lines from 34 patients using HemePACT_v3. Clinical data includes: Cancer Type, Mutation Count, Fraction Genome Altered, Sex, Collaboration Id, Oncotree Code, Specimen Preservation Type, Tissue Site. The plaintext components of the dataset can be downloaded as a tar file. The clinical...

Dataset Description from EGA: " Initial WGS of plasma cell neoplasms in fire fighters exposed to the WTC attack " There are 14 samples. Abstract of the article associated with the dataset for a further explanation: "Multiple myeloma (MM) is consistently preceded by precursor conditions recognized clinically as monoclonal gammopathy of undetermined significance (MGUS) or smoldering myeloma (SMM)....

This Dataset is a SuperSeries composed of the following SubSeries: GSE79639 Loss of CREBBP results in H3K27ac loss at enhancers in lymphoma cells GSE79640 Loss of CREBBP results in H3K27ac loss at enhancers in mouse lymphoma cells GSE79684 Loss of CREBBP results in gene expression repression in lymphoma cells GSE79685 Loss of CREBBP results in gene expression represssion in mouse lymphoma cells...

Summary from the GEO: "KD of CREBBP at lymphoma cell line, MD901, results in reduced H3K27ac enrichment at a subset of promoters and enhancers. Genome-wide H3K27Ac ChIPseq binding sites in human cell line MD901 (CREBBP wild type) with shCREBBP (11027 and 3752) and scramble control."

Summary from the GEO: "KD of CREBBP at lymphoma cell line, MD901, results in reduced expression. Genome-wide profiling of total RNA transcript levels in human cell line MD901 (CREBBP wild type) with shCREBBP and scramble control." The associated article further explains the study and shows how the dataset is connected: "Somatic mutations in CREBBP occur frequently in B-cell lymphoma. Here, we show...

Summary from the GEO: "KD of Crebbp at mouse cells results in reduced H3K27ac enrichment at a subset of promoters and enhancers. Genome-wide H3K27Ac ChIPseq binding sites in mouse cells with shCrebbp and scramble control."